Pregunta 1
Pregunta
Which options are primary lymphoid organs?
Respuesta
-
Thymus
-
Bone marrow
-
Spleen
-
Peyer's patches
-
MALT
Pregunta 2
Pregunta
Which options are secondary lymphoid organs?
Respuesta
-
MALT
-
Spleen
-
Lymph nodes
-
Thymus
-
Bone marrow
Pregunta 3
Pregunta
Dendritic cells are derived from lymphoid and myeloid precursors.
Respuesta
- True
- False
Pregunta 4
Pregunta
Platelets are derived directly from pluripotent stem cells.
Respuesta
- True
- False
Pregunta 5
Pregunta
Which options do not express MHC Class 1?
Respuesta
-
Red blood cells
-
Platelets
-
Neutrophils
-
B cells
-
T cells
Pregunta 6
Pregunta
Naive B cells are derived from the
Respuesta
-
Bone marrow
-
Thymus
-
Spleen
-
MALT
Pregunta 7
Pregunta
CD4+ T cells recognise
Respuesta
-
MHC Class 1
-
MHC Class 2
Pregunta 8
Pregunta
CD8+ T cells recognise
Respuesta
-
MHC Class 1
-
MHC Class 2
Pregunta 9
Pregunta
CD16 and CD56 are both found on
Respuesta
-
NK cells
-
Macrophages
-
B cells
-
T cells
Pregunta 10
Pregunta
All leukocytes express
Respuesta
-
CD45
-
CD19
-
CD68
-
CD59
Pregunta 11
Pregunta
The most abundant leukocyte in circulation are...
Respuesta
-
Neutrophils
-
Macrophages
-
B cells
-
CD8+ T cells
Pregunta 12
Pregunta
Monocytes and Macrophages help to produce components involved in the complement system
Respuesta
- True
- False
Pregunta 13
Pregunta
Macrophages are able to present antigens on their surface
Respuesta
- True
- False
Pregunta 14
Pregunta
Monocytes have CD.....
Respuesta
-
14
-
56
-
16
-
15
Pregunta 15
Pregunta
During phagocytosis, fusion of the lysosome and phagosome leads to production of...
Respuesta
-
Phagolysosome
-
Early endosome
-
Endophagosome
Pregunta 16
Pregunta
Which granulocytes have major basic protein in their granules?
Respuesta
-
Eosinophils
-
Basophils
-
Neutrophils
Pregunta 17
Pregunta
Which granulocytes have lactoferrin in their granules?
Respuesta
-
Neutrophils
-
Eosinophils
-
Basophils
Pregunta 18
Pregunta
Which granulocytes do not have histamine in their granules?
Respuesta
-
Eosinophils
-
Neutrophils
-
Basophils
Pregunta 19
Pregunta
Which granulocytes have chondroitin sulphate in their granules?
Respuesta
-
Neutrophils
-
Eosinophils
-
Basophils
Pregunta 20
Pregunta
Which of these are reactive oxygen species?
Respuesta
-
Hypochlorous acid
-
Hydrogen peroxide
-
Superoxide
-
Water
Pregunta 21
Pregunta
The only antimicrobial peptides that macrophages use are...
Respuesta
-
Cathelicidins
-
Azurocidin
-
Defensins
-
Histatins
Pregunta 22
Pregunta
Acidification by neutrophils or macrophages is...
Respuesta
-
Bacteriocidal
-
Bacteriostatic
-
Can be both
Pregunta 23
Pregunta
Both macrophages and neutrophils produce ROS's.
Respuesta
- True
- False
Pregunta 24
Pregunta
Both macrophages and neutrophils produce NETs.
Respuesta
- True
- False
Pregunta 25
Pregunta
The most potent antigen present cell is...
Respuesta
-
Dendritic cells
-
Macrophages
-
Monocytes
-
B cells
Pregunta 26
Respuesta
-
platelet
-
ctivating
-
fibrinogen
-
ytokines
-
C3b
Pregunta 27
Pregunta
Most T cells are...
Respuesta
-
CD4 positive but CD8 negative
-
CD4 positive and CD8 positive
-
CD8 positive but CD4 negative
Pregunta 28
Pregunta
Which cytokine results in a T cell receptor being produced on an immature T cell?
Respuesta
-
IL-7
-
IL-10
-
GM-CSF
-
TNF-a
Pregunta 29
Pregunta
Self molecules are said to induce...
Respuesta
-
Tolerance
-
Multi-specificity
-
Immunogenicity
Pregunta 30
Pregunta
What is negative selection?
Respuesta
-
T cells with a high affinity for self antigens are killed by apoptosis
-
T cells with a high avidity for self antigens are killed by apoptosis
-
T cells with a low affinity for self antigens are killed by apoptosis
-
T cells with a low affinity for self antigens are allowed to mature
Pregunta 31
Pregunta
What is positive selection?
Respuesta
-
T cells with a low affinity for self antigens are allowed to mature
-
T cells with a high affinity for self antigens are allowed to mature
-
T cells with a high affinity for self antigens are killed off by apoptosis
-
T cells with a low affinity for self antigens are killed off by apoptosis
Pregunta 32
Pregunta
The majority of T cells do not make it through negative selection.
Respuesta
- True
- False
Pregunta 33
Pregunta
T cells without any stimulation also die off.
Respuesta
- True
- False
Pregunta 34
Pregunta
What CD do T regulatory cells have?
Respuesta
-
4
-
19
-
8
Pregunta 35
Pregunta
Which cells do TH1 helper cells activate?
Respuesta
-
Macrophages
-
B cells
-
Any nucleated cell
-
Stromal cells
Pregunta 36
Pregunta
Which cells do TH2 helper cells activate?
Respuesta
-
B cells
-
Macrophages
-
T cells
-
Stromal cells
Pregunta 37
Pregunta
Which cells do TH17 helper cells activate?
Respuesta
-
Stromal cells
-
B cells
-
Macrophages
-
T cells
Pregunta 38
Pregunta
What is the main effect of T reg cells?
Respuesta
-
Recruiting neutrophils
-
Activating macrophages
-
Triggering B cell proliferation and antibody secretion
-
Inhibition of immune response
Pregunta 39
Pregunta
What is the main effect of TH2 cells?
Respuesta
-
Recruiting neutrophils
-
Activating macrophages
-
Triggering B cell proliferation and antibody secretion
-
Inhibition of immune response
Pregunta 40
Pregunta
What is the main effect of TH1 cells?
Respuesta
-
Recruiting neutrophils
-
Activating macrophages
-
Triggering B cell proliferation and antibody secretion
-
Inhibition of immune response
Pregunta 41
Pregunta
What is the main effect of TH17 cells?
Respuesta
-
Recruiting neutrophils
-
Activating macrophages
-
Triggering B cell proliferation and antibody secretion
-
Inhibition of immune response
Pregunta 42
Pregunta
Which cytokine(s) tend to be released by TH17 cells?
Respuesta
-
IL-7
-
IL-17
-
TGF-beta
-
IL-10
Pregunta 43
Pregunta
Which cytokine(s) tend to be released by TH1 cells?
Respuesta
-
IL-7
-
IL-10
-
IFN-gamma
-
TGF-beta
Pregunta 44
Pregunta
Which cytokine(s) tend to be released by TH2 cells?
Respuesta
-
IL-4
-
TNF-a
-
TNF-b
-
PGD2
Pregunta 45
Pregunta
Which cytokine(s) tend to be released by CD8+ cells?
Respuesta
-
IFN-gamma
-
TNF-a
-
TGF-b
-
IL-4
Pregunta 46
Pregunta
What feature on T cells helps to induce proliferation B cells?
Respuesta
-
CD40
-
CD40 Ligand
-
mIgM
-
CD45
Pregunta 47
Pregunta
B cells have complement receptors.
Respuesta
- True
- False
Pregunta 48
Pregunta
As well as perforin and granzyme to kill target cells, NK cells have...
Respuesta
-
NK Cytotoxic factor
-
CD40 Ligand
-
Major basic protein
-
Lyophosphatase
Pregunta 49
Pregunta
Interferon gamma is produced by NK cells - what is its function?
Respuesta
-
Activate phagocytes
-
Activates B cells
-
Induces proliferation of T cells
Pregunta 50
Pregunta
NK cells have a T cell receptor.
Respuesta
- True
- False
Pregunta 51
Pregunta
T cells are the most abundant lymphocytes.
Respuesta
- True
- False
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