Introduction to chemotherapy

Pregunta	Respuesta
Malignant Cell	Invade the surrounding tissue & spread throughout the body
Doubling time	Time taken for the tumor mass to double in size Need to be more than 1 cm to be detected
For chemotherapy to be successful	1. Tumor burden in low 2. Growth Fraction is high
Metastasis	1. Through blood 2. Through Lymphatic system
Goals of cancer treatment	1. Cure 2. Extend life 3. Release symptoms
Advantage of combination therapy	1. Maximum cell kill within acceptable toxicity 2. Broad coverage against cell lines 3. Slow emergence of resistant strains
Disadvantage of combination therapy	1. Expensive 2. Complicated to administer 3. Multiple toxicities with greater patient discomfort
Aim of chemotherapy	1. Palliative 2. Combination 3. Neoadjuvant (before surgery) Adjuvant (Post Operative)
Complete remission	Complete disappearance of tumour cell for at least 1 moth
Partial remission	1. More than 50% decrease of tumour 2. No evidence of progression
Disease Progression	1. Treatment Failure 2. Increase more than 25% 3. Appearance of new leisions
Stable disease	1. Tumour does not meet any criteria 2. Tumour does not increase in size

Resumen del Recurso

	Creado por sesamemonstersx hace alrededor de 12 años