Organic Chemistry Reaction Types

Pregunta	Respuesta
SN2 Leaving Groups	TosO, I, Br, Cl
SN2 Solvents	HMPA, CH3CN, DMF, DMSO Polar aprotic surround the cation but not the nucleophile
SN2 Substrates	Methyl, 1, 2, 3* due to steric hinderance and its role in mechanism
SN1 Substrates	3, 2=Benzyl=allylic, 1*, methyl
SN1 Leaving Group	H20, TosO=I, Br, Cl, OH Easily removable for carbocation formation
SN1 Nucleophile	Does not effect reaction rate Non basic to prevent elimination
SN1 Solvent	H2O, Water/Ethanol, Ethanol Stabilizes carbocation
E2 Definition	Alkyl Halide + Strong Base No intermediates Periplanar geometry non-Zaitsev product in rings
Zaitsev's Rule	More substituted alkene will form
E1 Reaction	Alkyl Halide + Strong Base Carbocation formed Base forces loss of adjacent hydrogen and formation of double bond
E1 and SN1 happen together with...	Protic solvent nonbasic nucleophile both reactions have the same preferable substrates
Primary Alkyl Halides	SN2 if good nucleophile (regular strong base, negative) E2 f strong sterically hindered base
SN2 Nucleophile	Basic, negatively charged nucleophiles

Resumen del Recurso

	Creado por aliroussel hace casi 12 años