Sickle Cell Anemia

Descripción

(Biology Exam 2) Mapa Mental sobre Sickle Cell Anemia, creado por izzy5605 el 22/10/2013.
izzy5605
Mapa Mental por izzy5605, actualizado hace más de 1 año
izzy5605
Creado por izzy5605 hace alrededor de 13 años
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Resumen del Recurso

Sickle Cell Anemia
  1. change in one nucleotide
    1. changes entire amino acid sequence
      1. changes structure of protein
        1. changes shape of red blood cell (sickle shape)
          1. protein misfolding
            1. some hydrophobic amino acids could be displayed on surface
              1. changes cell function
      2. inherited
        1. protein aggregation
          1. because of misfolding they clump together
          2. malaria
            1. one sickle cell mutation and one non mutated gene
              1. resistant to malaria
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