Antimicrobials (Unfinished)

Cell Wall Synthesis Agents
1. Beta-Lactams
  1. Cephalosporins
    1. 1st Generation
      1. Cephalexin (PO)
      2. Cefazolin (IV)
      3. Treats
        Gram positive aerobes
        Ideal for Streptococci and MSSA
    2. 2nd Generation
      1. Cefuroxime (IV, PO)
      2. Cefaclor (PO)
      3. Cephamycins
        Cefotetan IIV)
        Cefoxitin (IV)
        Only cephalosporins that treat Bacteroides (gut anaerobe)
    3. 3rd Generation
      1. Cefdinir (PO)
      2. Cefpodoxime (PO)
      3. Ceftriaxone (IV)
      4. Ceftazidime (IV)
        Pseudomonas aeruginosa (gram negative aerobe)
      5. Cefotaxime (IV)
    4. 4th Generation
      1. Cefepime (IV)
        Pseudomonas aeruginosa
    5. 5th Generation
      1. Cefaroline (IV)
        MRSA
    6. Gram negative activity increases with higher generations
    7. All but Ceftazidime treat Streptococcus pneumoniae (gram positive aerobe)
  2. Penicillins
    1. Natural Penicillins
      1. Penicillin G (IV)
      2. Penicillin V (PO)
      3. Treats
        Gram positive aerobes
        Streptococci, Enterococci
        Anaerobes
        Mouth anaerobes like Peptostreptococcus, Actinomyces
        Syphilis (DoC)
    2. Penicillinase-Resistant Penicillins
      1. Oxacillin (IV)
      2. Nafcillin (IV)
      3. Dicloxacillin (PO)
      4. Treats
        Gram positive aerobes
        Streptococci, Staphylococci (MSSA)
        MSSA better than vancomycin
    3. Aminopenicillins
      1. Ampicillin
        DoC for Listeria
      2. Amoxicillin
      3. Treats
        Gram positive aerobes
        Streptococci, Enterococci, Listeria
        Gram negative aerobes
        E. coli, Haemophilus, Proteus
    4. Antipseudomonal Penicillins
      1. Ticarcillin
      2. Piperacillin
    5. Extended Spectrum Penicillins/Beta-Lactamase Inhibitor Combinations
      1. Ampicillin/Sulbactam (IV)
        Actinobacter (hospital bug)
      2. Amoxicillin/Clavulanate (PO)
      3. Piperacillin/Tazobactam (IV)
        Pseudomonas, Enterobacter, Serratia, Morganella, Citrobacter
      4. Treats
        Gram positive aerobes
        Parent drug + MSSA
        Gram negative aerobes
        E. Coli, Klebsilla, Proteus, Haemophilus
        Anaerobes
        Mouth anaerobes like Fusobacterium, Prevotella, Bacteroides, & gut anaerobes like Bacteroides
  3. Carbapenems
    1. Imipenem
    2. Meropenem
    3. Ertapenem
    4. Doripenem
2. Monobactams
  1. Aztreonam
3. Lipoglycopeptides
  1. Telavancin
  2. Dalbavancin
  3. Oritavancin
4. Glycopeptides
  1. Vancomycin
  2. Bacitracin

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Antimicrobials (Unfinished)

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	Creado por Breanna Felldin hace más de 6 años