1. TRUE/FALSE - definitions and normal puberty.
A. The onset of puberty in females is defined as stage 1 breast development.

1. TRUE/FALSE - definitions and normal puberty.
B. The onset of puberty in males is defined as the appearance of pubic hair.

1. TRUE/FALSE - definitions and normal puberty.
C. Females enter puberty earlier than males.

1. TRUE/FALSE - definitions and normal puberty.
D. Peak height velocity occurs at stage 4 breasts in girls.

2. TRUE/FALSE - precocious puberty.
A. Central precocious puberty (CPP) is rarely pathological in males.

2. TRUE/FALSE - precocious puberty.
B. Low or undetectable gonadotropins in the presence of pubertal signs suggest pseudo (peripheral) precocious puberty.

2. TRUE/FALSE - precocious puberty.
C. CNS tumours can cause CPP.

2. TRUE/FALSE - precocious puberty.
D. The definition of CPP in females is stage 2 breast development before the 9th birthday.

3. TRUE/FALSE - normal variants.
A. Medical treatment is often required for premature thelarche.

3. TRUE/FALSE - normal variants.
B. Congenital adrenal hyperplasia (CAH) is often detected on routine baseline investigations for premature adrenarche.

3. TRUE/FALSE - normal variants.
C. Gynaecomastia always requires extensive investigation.

4. TRUE/FALSE - delayed puberty.
A. Pubertal delay may be associated with poor sense of smell.

4. TRUE/FALSE - delayed puberty.
B. High gonadotropins are suggestive of a primary gonadal problem.

4. TRUE/FALSE - delayed puberty.
C. Constitutional delay of growth usually requires medical treatment.