1045790
Description
Flashcards by sesamemonstersx, updated more than 1 year ago
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Created by sesamemonstersx
about 12 years ago
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| Question | Answer |
| Malignant Cell | Invade the surrounding tissue & spread throughout the body |
| Doubling time | Time taken for the tumor mass to double in size Need to be more than 1 cm to be detected |
| For chemotherapy to be successful | 1. Tumor burden in low 2. Growth Fraction is high |
| Metastasis | 1. Through blood 2. Through Lymphatic system |
| Goals of cancer treatment | 1. Cure 2. Extend life 3. Release symptoms |
| Advantage of combination therapy | 1. Maximum cell kill within acceptable toxicity 2. Broad coverage against cell lines 3. Slow emergence of resistant strains |
| Disadvantage of combination therapy | 1. Expensive 2. Complicated to administer 3. Multiple toxicities with greater patient discomfort |
| Aim of chemotherapy | 1. Palliative 2. Combination 3. Neoadjuvant (before surgery) Adjuvant (Post Operative) |
| Complete remission | Complete disappearance of tumour cell for at least 1 moth |
| Partial remission | 1. More than 50% decrease of tumour 2. No evidence of progression |
| Disease Progression | 1. Treatment Failure 2. Increase more than 25% 3. Appearance of new leisions |
| Stable disease | 1. Tumour does not meet any criteria 2. Tumour does not increase in size |
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