Cluster de diferenciación CD1-CD50

Description

Se muestra el CD con el nombre común, si es que aplica. La platilla muestra en la parte superior las células en que se expresa y en la parte inferior la función.
Luis Miguel  Barajas Castañeda
Flashcards by Luis Miguel Barajas Castañeda, updated more than 1 year ago
Luis Miguel  Barajas Castañeda
Created by Luis Miguel Barajas Castañeda over 6 years ago
22
0

Resource summary

Question Answer
CD1 Cortical thymocytes, Langerhans cells, dendritic cells and certain T-cell leukemias. Non-peptide antigen presentation to T-cell receptors on NKT cells, marks
CD1b Cortical thymocytes, Langerhans cells and dendritic cells. Non peptide antigen presentation to T-cell receptors on NKT cells.
CD1c Cortical thymocytes, Langerhans cells, dendritic cells and B-cell subsets. Non peptide antigen presentation to T-cell receptors on NKT cells.
CD1d R3G1 Intestinal epithelial cells, B-cell subsets, cortical thymocytes, dendritic cells and certain T-cell leukemias. Non peptide antigen presentation to T-cell receptors on NKT cells.
CD1e R2G1 Cortical thymocytes, Langerhans cells, dendritic cells and certain T-cell leukemias. Non peptide antigen presentation.
CD2 SRBC, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor Thymocytes, natural killer cells, T- and B-cells. Adhesion between T-cells and other cell types and T-cell activation.
CD3d T3D, OKT3 Mature T-cells and thymocytes. T-cell activation signaling and regulation of TCR expression.
CD3e T3E, TCRE Mature T-cells and thymocytes. T-cell activation signaling and regulation of TCR expression.
CD3g T3G Mature T-cells and thymocytes. T-cell activation signaling and regulation of TCR expression.
CD4 Thymocyte subsets, T-helper cells, regulatory T-cells, monocytes and macrophages. T-cell activation, thymic differentiation and receptor for HIV.
CD5 LEU1 Thymocytes, T- and B-cell subsets and B-cell chronic lymphocytic leukemia cells. Regulates T-cell: B-cell interactions. Interacts with CD72.
CD6 OX52, T12, TP120 Thymocytes, T- and B-cell subsets and neuron subsets. Thymocyte development, a potential market of T-cell activation.
CD7 LEU 9, GP40, TP41 Thymocytes, T-cells, natural killer cells and pluripotent hematopoietic stem cells. T-cell costimulation. Interacts with SECTM1.
CD8a MAL Thymocyte subsets, cytotoxic T-cells, natural killer cells and dendritic cells subsets. Co-receptor for MHC class 1 molecules.
CD8b CD8B1 Thymocyte subsets and cytotoxic T-cells. Co-receptor for MHC class 1 molecules.
CD9 P24, 5H9 antigen, MIC3, TSPAN29, GIG2 Platelets, pre-B-cells, eosinophils, basophils, activated T-cells, endothelial cells and epithelial cells. Cell adhesion and migration, platelet activation and aggregation.
CD10 Neprilysin, CALLA, SFE, MME, EPN B- and T-cell precursors, fibroblasts, neurons and bone marrow stromal cells. Peptidase, regulates B-cell growth.
CD11a Integrin alpha-L, LFA-1A, ITGAL Leukocytes, lymphocytes, granulocytes, monocytes and macrophages. Intracellular adhesion and costimulation.
CD11b Integrin alpha-M, CR3A, ITGAM Granulocytes, monocytes, natural killer cells, T- and B-cells and dendritic cells. Cell adhesion, apoptosis and chemotaxis.
CD11c Integrin alpha-X, Leu M5, ITGAX Monocytes, macrophages, granulocytes, T- and B-cell subsets. Cell adhesion.
CD11d Integrin-alpha-D, ADB2, ITGAD Myelomonocytic cells, peripheral blood leukocyte subsets and tissue-specialized cells. Receptor for ICAM3 and VCAM1. May play a role in atherosclerotic process and phagocytosis of blood-borne pathogens.
CD13 Aminopeptidase N, ANPEP, APN, PEPN Granulocytes, monocytes (+ precursors), endothelial cells and epithelial cells. Zinc binding metalloproteinase.
CD14 Monocytes, macrophages (myelomonocytic cells), Langerhans cells and granulocytes. Receptor for complex of LPS and LBP.
CD15 3-FAL, ELAM 1 ligand, fucosyltransferase, Leu M1 Granulocytes, monocytes, neutrophils and eosinophils. Cell adhesion. Mediates phagocytosis and chemotaxis.
CD16a Fc-gamma RIII-alpha, FCGR3A, FCG3, FCGR3, IGFR3 Neutrophils, natural killer cells and macrophages. Low affinity Fc receptor. Mediates phagocytosis and ADCC.
CD16b Fc-gamma RIII-beta, FCGR3B, FCG3, FCGR3, IGFR3 Neutrophils and stimulated eosinophils. Low affinity Fc receptor.
CD17 Lactosylceramide Monocytes, platelets, B-cell subsets, granulocytes, dendritic cells, T-cells, platelets, neutrophils and thrombocytes. Lactocyl ceramide. Cell surface glycosphingolipid. May play a role in bacterial phagocytosis.
CD18 Integrin beta-2, ITGB2, MFI7 Leukocytes. Forms the beta 2 chain of CD11a-c, cell adhesion.
CD19 B-lymphocyte surface antigen B4, T-cell surface antigen Leu-12 B-cells (but not plasma cells) and follicular dendritic cells. Regulates B-cell development, activation and differentiation. Signal transduction.
CD20 B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, MS4A1 T- and B-cell subsets. B-cell activation and proliferation.
CD21 Complement receptor type 2, CR2, C3DR, Complement C3d receptor, Epstein-Barr virus receptor Mature B-cells, follicular dendritic cells and T-cell subsets. Signal transduction. Receptor for complement components C3Dd and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220.
CD22 SIGLEC2, BL-CAM, T-cell surface antigen Leu-14 Mature B-cells. B-cell adhesion and signal transduction.
CD23 Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, Fc epsilon RII, FCER2, CLEC4J Mature B-cells, activated macrophages, eosinophils, follicular dendritic cells and platelets. Low affinity receptor for IgE, ligand for CD19, CD21 and CD81.
CD24 Nectadrin B-cells, granulocytes, epithelial cells and monocytes. Regulation of B-cell proliferation and differentiation.
CD25 Interleukin-2 receptor subunit alpha, IL2RA, TAC antigen Activated T- and B-cells, some thymocytes, pre B-cells, regulatory T-cells, and oligodendrocytes. Receptor for IL2.
CD26 Dipeptidyl peptidase 4, DPP4 , ADABP, ADCP2 Mature thymocytes, T-cells (upregulated on activation), activated B-cells, natural killer cells, epithelial cells and macrophages. Exoprotease. HIV pathogenesis.
CD27 TNF receptor superfamily member 7, TNFRSF 7, CD27L receptor, T14 T-cells, medullary thymocytes, B-cell subsets and natural killer cells. Costimulation of B- and T-cell activation.
CD28 TP44 Most T-cells, thymocytes, plasma cells, natural killer cells and activated B-cells. Costimulation of T-cells. Induces T-cell activation and survival, interleukin-2 production, T-helper type 2 cell development and clonal expansion.
CD29 Integrin beta-1, ITGB1, Fibronectin receptor subunit beta, FNRB Leukocytes. Interacts with CD49a in VLA-1 integrin. Lymphocyte and endotelial adhesion, lymphocyte trafficking and transvascular migration. Promotes or inhibits apoptosis (depending on stimulus).
CD30 TNF receptor superfamily member 8, TNFRSF8, Ki-1 antigen Activated T- and B-cells, monocytes, activated natural killer cells and Reed-Sternberg cells. Regulates lymphocyte proliferation and cell death. Has a critical role in the pathophysiology of Hodgkin’s disease and other CD30+ lymphomas.
CD31 Platelet endothelial cell adhesión molecule, PECAM1 Monocytes, platelets, granulocytes, endothelial cells, lymphocyte subsets and epithelial cells. Cell adhesion. Plays a key role in leukocyte trafficking across endothelium
CD32 Fc gamma RII, FCGR2A, FCGR2B B-cells, monocytes, granulocytes, platelets and endothelial cells. Regulation of B-cell function. Induces phagocytosis and mediator release.
CD33 Sialic acid-binding Ig-like lectin 3, SIGLEC3 Monocytes, granulocytes, mast cells and myeloid progenitors. Lectin activity and adhesion. A receptor that inhibits the proliferation of normal and leukemic myeloid cells.
CD34 Hematopoietic stem cells and progenitors and capillary endothelial cells. Cell adhesion (via L-selectin). Possible role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracelular matrix or directly to stromal cells.
CD35 Complement receptor type 1, C3b/C4b receptor Erythrocytes, B-cells, monocytes, neutrophils, eosinophils, follicular dendritic cells and T-cell subsets. Receptor for complement components C3b and C4b. Mediates adhesión and phagocytosis.
CD36 Platelet glycoprotein 4, Fatty acid translocase, Glycoprotein IIIb GP3B, GP4 Platelets, monocytes, macrophages, endothelial cells and thyroid precursors. Scavenger receptor preferentially found within lipid rafts. Mediates adhesion and phagocytosis.
CD37 Tetraspanin 26, TSPAN26 Mature B-cells and myeloid cells. Low level of expression in T-cells, granulocytes and monocytes. Signal transduction. Regulates T-cell proliferation.
CD38 ADP ribosyl cyclase 1 Variable expression levels on most hematopoietic and some non-hematopoietic cells. High levels on plasma cells, early T- and B-cells, activated T-cells and germinal centre B-cells. Regulates cell activation, proliferation and adhesion.
CD39 NTPDase 1, ENTPD1 Macrophages, Langerhans cells, dendritic cells, activated B-cells, natural killer cells and microglial cells. B-cell adhesion. Protects activated cells from lysis.
CD40 TNF receptor superfamily member 5, TNFRSF5 B-cells, monocytes, macrophages, follicular dendritic cells, endothelial cells, fibroblasts and keratinocytes. Costimulation of B-cell growth. Differentiation and isotype switching.
CD41 Integrin alpha-IIb, GPalpha IIb, ITGA2B, GP2B Platelets and megakaryocytes. Platelet activation and aggregation.
CD42a Platelet glycoprotein IX, GP9 Platelets and megakaryocytes. Platelet adhesion and aggregation. Amplifies platelet response to thrombin
CD42b Platelet glycoprotein Ib alpha chain, GP1BA Platelets and megakaryocytes. Platelet adhesion and aggregation.
CD42c Platelet glycoprotein Ib beta chain, GP1BB Platelets and megakaryocytes. Platelet adhesion and aggregation.
CD42d Platelet glycoprotein V, GP5 Platelets and megakaryocytes. Platelet adhesion and aggregation.
CD43 Leukosialin, Galactoglycoprotein, Leukocyte sialoglycoprotein, SPN Leukocytes (except resting B-cells). Low expression in platelets. Anti-adhesion. Binds CD45 to mediate adhesion.
CD44 Epican, HUTCH-I, LHR, PGP-1, ECMR-III Most lymphohematopoietic cells. Leukocyte rolling, homing and aggregation. Adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. Important in epithelial cell adhesion (cell-cell and cell-matrix) to hyaluronate in basement membranes, and maintaining polar orientation of cells.
CD45 Leukocyte common antigen, L-CA, PTPRC Hematopoietic cells (not erythrocytes and platelets). Critical for B- and T-cell receptor mediated activation. Also required for thymic selection.
CD45RA B- and naïve T-cell subsets, monocytes and medullary thymocytes. Critical for B- and T-cell receptor mediated activation. Also required for thymic selection.
CD45RB T-cell subsets, B-cells, monocytes, macrophages, granulocytes, dendritic cells and natural killer cells. Critical for B- and T-cell receptor mediated activation.
CD45RC B-cells, natural killer cells, CD8+ T-cells, CD4+ T-cell subsets, medullary thymocytes, monocytes and dendritic cells. Critical for B- and T-cell receptor mediated activation.
CD45RO Activated T-cell subsets, memory B- and T-cell subsets, monocytes, macrophages, granulocytes, cortical thymocytes and dendritic cell subsets.
CD46 Membrane cofactor protein, TLX, MCP Ubiquitous except erythrocytes. Co-factor for factor 1 proteolytic cleavage of C3b and C4b. Sets protective barrier threshold against inappropriate complement activation.
CD47 Integrin associated protein, MER6 Hematopoietic cells, epithelial cells, endothelial cells and mesechymal cells. Adhesion. A marker of self which binds to SIRP alpha inhibitor receptor on macro and dendritic cells to inhibit phagocytosis. Regulates chemotaxis and activation of leukocytes.
CD48 BLAST1, BCM1 Leukocytes. Cell adhesion and T-cell costimulation.
CD49a Integrin alpha-1, VLA-1, ITGA1 Activated T-cells, monocytes, melanoma cells and endothelial cells. Adhesion and embryo development.
CD49b Integrin alpha-2, VLA-2 subunit alpha, ITGA2 Platelets, B-cells, monocytes, activated T-cells, epithelial cells, endothelial cells, natural killer cell subsets and megakaryocytes. Adhesion and platelet aggregation. Receptor for echovirus 1.
CD49c Integrin alpha-3, VLA-3 subunit alpha, ITGA3 Most adhesion cell lines. Low expression on B- and T-cells. Adhesion and signal transduction.
CD49d Integrin alpha-4, VLA-4 subunit alpha, ITGA4 B- and T-cells, thymocytes, monocytes, eosinophils, basophils, natural killer cells, mast cells, dendritic cells and erythroblastic precursors. Adhesion, cell migration, homing and activation.
CD49e Integrin alpha-5, VLA-5, ITGA5 Thymocytes, T-cells, monocytes, platelets, early and activated B-cells, endothelial cells and epithelial cells. Adhesion, regulation of cell survival and apoptosis.
CD49f Integrin alpha-6, VLA-6, ITGA6 Memory B-cells, T-cells, thymocytes, monocytes, platelets, megakaryocytes, epithelial cells, endothelial cells and cytotrophoblasts. Embryogenesis, adhesion and cell migration.
CD50 ICAM3 Leukocytes, thymocytes, Langerhans cells, endothelial cells, B- and T-cells, granulocytes and monocytes. Adhesion and costimulation.
Show full summary Hide full summary

Similar

DISPOSITIVOS DE ALMACENAMIENTO
Emiliano Garita
Investigacion Cd
César Melgoza
AQA Sociology AS level
rhian-hay
AS-Level Chemistry: Unit 1:The Atom
Daena Targaryen
Command or Process Words for Essay Writing
Bekki
PE - GCSE Glossary
rjapmann
Chemistry revision
Jordyn Niu
Système circulatoire sanguin
Martin Fortier
1PR101 2.test - Část 18.
Nikola Truong
Core 1.12 Timbers blank test
T Andrews