Purines and pyrimidines

Question	Answer
functions of purines and pyrimidines	● constitutes vital structural units of nucleic acids( portion of complex substrate molecules) ● functions as coenzymes ●
description of purines	constitute heterocyclic nucleus of 6 membered pyrimidines and 5 membered imidazole
pyrimidines and imidazole	they are heterocyclic aromatic compounds ( contains 2 each, ring and double bonds) □ pyrimidines - 6 membered, 3 double bonds □ imidazole - 5 membered and 2 double bonds
example of purines	- guanine - cytosine - xanthin - hypoxanthin
example of pyrimidine	cytosine thyrosine uracil
biological existence of purines	it doesn't occur normally in nature but due to its numerous derivates in nature,it should be discussed
pharmacological important base of these groups is	xanthin 3, 7 dihydropurine 2, 6 dione derivatives include caffeine, theobromine, theophyline
caffeine	1, 3, 7 trimethyl xanthine
theophyline	1, 3 dimethyl xanthine
theobromine	3, 7 dimethyl xanthine
origin of atoms in xanthine backbone	◇carbon 2 and 8 from formate or methionate or compounds that can fragment to give active 1 carbon e.g glycine, serine ◇ carbon 6 from CO2 ◇ Carbon 4, 5 and Nitrogen 7 from glycine ◇ Nitrogen 1 from aspartate ◇ Nitrogen 3 and 9 from amide N in glutamate
test for purine and derivatives	Murexide test

Resource summary

	Created by Ajala marvellous about 6 years ago