EdExcel GCSE - Biology - Topic 5 - Health and Disease

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GCSE Biology Flashcards on EdExcel GCSE - Biology - Topic 5 - Health and Disease, created by Malachy Moran-Tun on 15/10/2020.
Malachy Moran-Tun
Flashcards by Malachy Moran-Tun, updated more than 1 year ago
Malachy Moran-Tun
Created by Malachy Moran-Tun over 3 years ago
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Question Answer
What is the WHO's Definition for Health? "a state of complete physical, mental and social well-being, and not merely the absence of disease or infirmity" (being weak or frail, usually because of old age)
What is a Communicable Disease? Diseases that can Spread between Individuals
What is a Non-Communicable Disease? Diseases that CAN'T be Transmitted between Individuals (eg. Cancer, Heart Disease)
What are Communicable Diseases caused by? Pathogens
What are Pathogens? Organisms such as viruses, bacteria, fungi and protists
Describe Ebola and its Transmission between Individuals > Virus > Hæmorrhagic fever (a fever with bleeding) > Spread via bodily fluids > Transmission can be reduced by quarantining individuals and sterilising areas
Describe Chalara Ash Dieback and its Transmission between Individuals > Fungal disease > Symptoms included leaf loss and bark lesions > Carried through the air by wind > Transmission can be reduced by removing young and infected trees or restricting the import of ash trees
Describe Malaria and its Transmission between Individuals > Protist > Symptoms include damage to red blood cells and liver > Mosquitoes act as animal vectors (carriers); they pass on to humans but don't get infected > Transmission can be reduced by mosquito nets and insect repellant
Describe Cholera and its Transmission between Individuals > Bacterium called Vibrio choleræ > Symptoms include diarrhœa > Spreads via contaminated water >Transmission can be reduced by access to clean water
Describe Tuberculosis and its Transmission between Individuals > Bacterium called Mycobacterium tuberculosis > Symptoms include coughing and lung damage > Spreads through the air via coughing (hello COVID my old friend) > Transmission can be reduced by avoiding crowded places, good hygiene and good ventilation
Describe (some) Stomach Ulcers and its Transmission between Individuals > Bacterium called Helicobacter pylori > Symptoms include stomach pain, nausea and vomiting > Spread through oral transmission ( ͡° ͜ʖ ͡°) > Transmission can be reduced by clean water and good hygiene
What are STIs? Sexually Transmitted Infections that are spread through the saucy times... including the ultimate saucy time (sexual intercourse) ( ͡° ͜ʖ ͡°)
Describe Chlamydia and its Transmission between Individuals > Bacterium BUT behaves like a virus (makes perfect sense) > Symptoms not always shown but can cause infertility > Reduced by wearing a condom when having the saucy times ( ͡° ͜ʖ ͡°), testing individuals and avoiding sexual contact
Describe HIV and its Transmission between Individuals > Human Immunodeficiency Virus > Symptoms include killing white blood cells > Eventually leads to AIDS (Acquired Immune Deficiency Syndrome) > AIDS causes the immune system to deteriorate > Spread via bodily fluids (eg. ( ͡° ͜ʖ ͡°), blood, ( ͡° ͜ʖ ͡°)) > Transmission can be reduced by wearing a condom, not sharing needles you druggos and screening
What are Viruses? > NOT CELLS > Protein coat around a strand of genetic material > Have to infect living cells to reproduce (host cells) > Life cycle starts when it infects a new host cell > Reproduce by lytic pathway, but some enter the lysogenic pathway first
What is the Lytic Pathway? > Virus attaches to a specific host cell > Injects genetic material into the cell > Proteins and enzymes replicate the genetic material to produce components of new viruses > Components: Assemble > Host cell splits, releasing new viruses
What is the Lysogenic Pathway? > Injected genetic material is incorporated into the genome (DNA) > Viral genetic material is replicated along with the DNA every cell division > Virus is dormant, no new viruses are made > Eventually a trigger (a chemical) causes the genetic material to leave the genome and enter the lytic pathway
What are 2 Ways Plants Physically Defend against Pathogens and Pests? 1. Waxy cuticle as a barrier 2. Cell walls (made of cellulose) as another barrier
What are 2 Ways Plants Chemically Defend against Pathogens and Pests? 1. Antiseptics kill bacterial and fungal pathogens. 2. Other chemicals deter pests from feeding on their leaves
What are 2 Examples of Plant Chemicals used as Drugs to Treat Human Diseases? 1. Quinine - Bark of the cinchona tree 2. Aspirin - Developed from a chemical found in willow trees (bark & leaves)
What are 3 Ways Humans Physically Defend against Pathogens and Pests? > Skin acts as a barrier to pathogens (blood clots to seal cuts to keep this barrier) > Hairs and mucus trap particles that could contain pathogens > Cells in airways to lungs produce mucus and have cilia (hair like extensions)
What are 2 Ways Humans Chemically Defend against Pathogens and Pests? > Stomach produces Hydrochloric Acid > Eyes produce Lysozyme
What is the Main Type of Cell in the Immune System? White Blood Cells, specifically, B-Lymphocytes
What happens when B-Lymphocytes detect a Pathogen? > Pathogens have antigens > Antibodies produced which lock on to the pathogen > Antibodies rapidly produced and flow around the body to find similar pathogens
What is the role of Memory Lymphocytes? To give Immunity to Later Infections
How do Memory Lymphocytes Work? > Produced when antibodies are produced > Remain in the body for a long time and "remember" a specific antigen > Body responds quicker to a second infection > Secondary immune response becomes faster and stronger > Usually gets rid of pathogen before symptoms
What is Immunisation? Injecting dead or inactive pathogens to produce antibodies and memory lymphocytes
What are the Pros of Immunisation? > Outbreaks of diseases (epidemics / pandemics hello COVID my old friend again) can be stopped (herd immunity) > Some diseases have been virtually wiped out (until Karen said no) (no one likes Karen)
What are some Cons of Immunisation? > Isn't 100% effective > Reactions (including swelling, fevers or shower dances (seizures)) > Karen
What are Monoclonal Antibodies? > B-Lymphocytes fused with a tumor cell (myeloma cell) creating a hybridoma > Hybridomas can be cloned to get identical cells > Cells produce the same Monoclonal Antibodies > Monoclonal Antibodies can bind to any molecule
Pregnancy Tests and other uses of Monoclonal antibodies in Guide of Revision Making bonjourno. you appear to have flipped over a useless card. how embarrassing. you should be ashamed of your ignorance. anywai, i suppose you're just gonna go ahead and ignore this. well FINE. i DON'T CARE >:D
What are Antibiotics? A type of medicine that inhibits processes in bacterial cells, but NOT in the host organism (for example stopping the building of cell walls) They DO NOT destroy viruses
What happens in Preclinical Testing? > Drugs are tested on human cells and tissues in a lab > Drugs are then tested on live animals
What happens in Clinical Testing? > Drug is tested on human volunteers > Healthy then ill > Placebo and new drug tested
Bacteria practicals in revision guide https://www.youtube.com/watch?v=dQw4w9WgXcQ
What are Risk Factors? Factors that are linked to an increase in the likelihood that a person will develop a certain disease during their lifetime
What are some Examples of Risk Factors? > Smoking > Incomplete Diets > Not enough Exercise > Alcohol (whoopsies)
How do you Calculate BMI? BMI = mass (kg) ÷ height² (m)
What is Cardiovascular Disease? > Associated with heart and blood vessels > Cholesterol build up in fatty deposits > Restricts blood flow > Trigger blood clots which can block blood flow > Oxygen deprivation (not of the good unless you're a plant i guess)
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