C&B: Vasomotor Tone

Eng O-charoenrat
Flashcards by Eng O-charoenrat, updated more than 1 year ago
Eng O-charoenrat
Created by Eng O-charoenrat about 5 years ago
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Factors determining differences in vasomotor tone
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Question Answer
Vasoconstriction: 1 - Humoral Control 2- Vascular Endothelium (E.T.) 3- ANS Sympathetic 4 - Autoregulation 1 - Ang II, ADH 2 - Thromboxane A2, Endothelin 3 - Alpha-1 4 - Shear forces, Intraluminal pressure
Vasodilation: 1 - Local Metabolic O2 Demand 2 - Vascular Endothelium (BEN P.) 3 - ANS Parasympathetic 4 - Autoregulation 1 - Hypoxia -> Adenosine, K+ build-up 2 - Bradykinin, EDRF, NO, Prostacyclin 3 - Beta-2, Muscarinic 4 - Shear forces, Intraluminal pressure
Vasoconstriction (4 factors) 1 - Humoral Control 2 - Vascular Endothelium 3 - ANS Sympathetic 4 - Autoregulation
Vasodilation (4 factors) 1 - Local Metabolic O2 Demand 2 - Vascular Endothelium 3 - ANS Parasympathetic 4 - Autoregulation
Vascular Endothelium: Vasoconstriction (E.T.) vs Vasodilation (BEN. P) Vasoconstriction - Endothelin, Thromboxane A2, Vasodilation - Bradykinin, EDRF, NO, Prostacyclin
ANS Responses: Vasoconstriction vs Vasodilation Vasoconstriction - Sympathetic Alpha-1 Vasodilation - Parasympathetic Beta-2 + Muscarinic
Vasoconstriction: Humoral Response ADH, Ang II
Vasodilation: Local Metabolic O2 Demand - Hypoxic cells - release adenosine = vasodilator - K+ build-up = K/ATP channel open = vasodilator
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