Step 3 - Obstetrics

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Flashcards on Step 3 - Obstetrics, created by moradnasseri on 17/05/2016.
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Jaimie Shah
Created by Jaimie Shah over 10 years ago
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Question Answer
when is gestational sac present on US 4-5 weeks with HCG>1500
when is fetal heart motion seen 5-6wks on US
fetal heart sounds heard with doppler US at 8-10wks
fetal movements felt when after 20wks gestation
review first tirmester screening chart pg 378 and 379
review second trimester screening table pg 380
inc MS-AFP NTD, ventral wall def, twin preg, placental bleed,renal dz, sacrococcygeal teratoma
dec in MS-AFP trisomy 21 and 18
dec MS-AFP, dec estriol, inc BHCG trisomy 21
trisomy 18 MS AFP, Estriol and B HCG all low
if dating is correct and MS AFP is elevated what next? do amiocentesis for acholinesterase activity and if high then spp of NTD
if dating correct and MSAFP low what to do next? do amiocentesis for karyotyping
review routine third trimester testing p. 381
Antiemetics safe in pregnancy Doxylamine, Metoclopramide, Ondansetron, Promethazine, Pryidoxine
cause of bleeding after 20wks gestation abruption (painful), placenta previa (painless), Vasa previa (painless), lower genital tract laceration or uterine rupture (painful).
late decels and bradycardia are seen in fetal compromise when? the fastest in bleed with vasa previa because the blood comes from fetal circulation first
when do you give Rhogam in negative mothers 28 wks, within 72hrs of delivery, after miscarriage and abortion, during amiocentesis or CVS adn with heavy vaginal bleed
never perform an exam on preg woman with late preg bleed till you do US to r/o placenta previa true
inital mgmt steps for late preg bleed get vitals, fetal monitor, IVFs, CBC, DIC panel, type and cross, US, transfuse, place foley, vaginal exam after US, delivery if more than 36wks
clue to dx of abruption if the bleeding is concelaed scan amount of bleeding with constant abd pain. DIC is a feared complication and can be reduced with amniotomy and induction of labor
vasa previa when fetal vessels lye past the cervix so when ROM occurs the fetus loses bloods as it's vessels are ruptured
so if mother in labor and no ROM do an US... if you see the vessels cross the cervix do not Rupture membranes because you will rupture the vessels.
placenta accreta<increta<percreta listed in increasing depth of invasion of the uterine wall
signs of urterine rupture loss of electronic fetal heart rate, uterine contractions, and recession of fetal head.
review table of late trimester bleeding causes pg 385
tx of GBS intrapartum Pen G IV, or IV cefazolin, clinda, or erythromycin; GBS causes PNA/sepsis in first hours/days and after first week menegitis but this is hosp acquired no from the mother
when do we give abx for GBS GBS + urine, cervical, vag cx, preterm del, ROM>18hrs, maternal fever, prior baby with GBS sepsis
when do you not give abx for GBS planned c section and no ROM but + culture; cx + in past but negative now
congenital toxo triade chorioretinitis, IC calcifications, hydrocephalus
RF or toxo handle cat feces/litter, drink raw milk or eating raw meat
prevent toxo avoid exposure and spiramycin to prevent vertical transmission
dx of toxo check IGM and if IGG avidity low then recent infection so she needs pyrimethamine and sulfadiazine
biggest risk factor for varicella passing to the infant from mother if mother has rash 5 days before delivery and 2 days after delivery
s/s of neonatal varicella infection zigzag skin lesion, limb hypoplasia, microcephaly, micophthalmia, chorioretinitis, cataracts.
prevent varicella to the neonate vaccinate non preg women, and VZVIg or antibody within 10d of exposure (attenuates effects doens't prevent)
maternal varicella treatement Varicella ab to mother and neonate
congenital varicella Ig and acyclovir to the neonate
congenital rubella adverse effects occur with primary infection in the first 10wks of gestation
S/S of congenital rubella cataracts, MR, hepatosplenomegaly, low plts, bluberry muffin rash
prevention of congenital rubella screen in first trimester, avoidance, immunize after delivery, no post exp ppx
CMV is the most common cause of what in the US SN hearing loss
about 10% of infants have symptomatic CMV at birth, S/S? IUGR, preme, microcephaly, jaundice, petechiae, hepatospelnomegaly, Periventriccular calcifications, chorioretinitis, and PNA
in mother check IGG and IGM for CMV and check viral culture from urine or body fluids in first 2wks of life and PCR true
tx CMV ganciclovir can prevent shedding and hearing loss; but not a cure of infection; IG can help in reducing spread from exp preg woman
only two active disease warrant C-section HIV and HSV
neonatal HSV infection 50%mortality, and if live have meningoencephalitis, MR, PNA, hepatosplenomegaly, jaundice, petechiae
other prevention of HSV avoid intercouse if partner has it, avoid oral sex if partner has oral lesions and avoid kissing neonate if anyone has oral lesions
acyclovir is treatment in primary infection in patient true
prevent passing of HIV to neonate elective C section for low CD4 and viral load>1000; false positive neontate at first; triple therapy must include ZDZ, no breast feed, no AROM
HIV prevention in neonate ZDZ based ART for 6wks after delivery, PCP ppx and continue for 6wks past ART therapy
there is no immunity from syphillus infection and reinfection can always happen true
can pass to baby if primary or secondary and much lower with tertiary or latent syphilis true
syphilis acquired in first trimester s/s nonimmune hydrops fetalis, maculopaupular rash, anemia, low plts, hepatosplenomegaly, edematout placenta, perinatal mortality 50%
late acq syphilis s/s appear at 2 yrs of age hutchinson teeth, mulberry molars, saddle nose, saber shins, deafness
c section prevents spread of congenital syphilis false
dx of syphilis VDRL or RPR screen and confirm with FTA-ABS or MHA-TP; screen neg in primary syphilis so bx ulcer with darkfield
tx syphilis in mothers IM benzathine PCN x1
how do neonates contract HBV from primary infection in 3rd trimester or ingest genital secretions; 80% will develop chronic hep unlike adults where only 10% contract chronic hep
if mothers are e antigen positve what percent risk is there for passage..and if not what is the percent to pass hep to the baby? 80%, if not then 10% passage risk
prevent spread to neonate of hep B not c section, avoid invasive procedures (amiocetesis), can breastfeed after baby gets HBIG; to mother give immunization if HBsAg neg and post exp ppx with antibodies to hep B (Ig)
tx of hep in infant immunize and HBIG; chronic treat with interferon or lamivudine
review breakdown of HTN in pregnancy pg 394 and 395
never give ACE i of thiazides in preg to control BP true
HELLP can occur... in the third trimester and pospartum as well (2days after delivery)
risk factor of HELLP different from preeclampsia whites, multigravids and women of older maternal age
tx of HELLP immediate del, IV decadron before and after del if plt<100,000 till >100,000; transfuse plt is<20,000 or <50,000 and to get C section; Mag even if BP nl to prevent seizures; steroids for fetal lung development may be needed.
complications of HELLP DIC, abruption, fetal demise, ascites, hepatic rupture
never use an ACE I or ARB during pregnancy true
loop diuretics, nitrates, BB may be continued true
digoxin can be used to control HF symps in pregnancy but it does not effect outcome true
use rate control in preg patients; do not give amiodarone or coumadin true
Endocarditis ppx is the same as nonpreg pts, don't need ppx for actual delivery or c section true
regurgitant lesions are fine in preg but stenotic lesions are exacerbated and increase materal/fetal mortality true
mital stenosis in preg has increased risk pulm edema and afib true
PE is leading cause of maternal death in US; 50% who get it have a hypercoagulable disease...when do we give DVT/PE ppx afib with heart disease (but not lone afib), Antiphospholipid syndrome, HF with EF<30%, Eisenmenger syndrome
in patient with prior history or reason of anticoagulation what do we give? ppx LMWH; intrapartum unfractioned heparin, and coumadin 6wks postpartum
hyperthyroid in preg causes FGR and still birth
hypothyroid in preg causes intellectual def and miscarriage
preg does not effect S/S of hyper or hypothyroidism and normal lab values of free T4/TSH true
increase thyroid hormone dose in hypothyroid in preg by 25-30% true
drug of choice for hypothyroid in preg synthroid
symptomatic hyperthyroid use BB not radioactive iodine
tx grave's dz in preg PTU may cause hypothroid in fetus; congenital graves can be masked for until 7-10d after birth
maternal TSIG can cross the placenta and cause fetal tachy, FGR, goiter
target BS in preg FBS<90 and <120 1 hr after a meal
Diabetes mgmt in preg start with lifestyle changes, add insulin if no control, avoid oral agents when breast feeding can cause fetal hypoglycemia
routine monitoring in preg patients A1c each trimester if elevated in first trimester: US 18-20wks, fetal echo 22-24wks. triple screen 16-18wks, monthly US, monthly BMP, wkly NST/AFI at 32wks
GDM post partum care check 2 hr 75g OGTT at 6-12wks postpartum; 35% develop over DM 5-10yrs after delivery
rare congenital abn in over DM mother caudal regression syndrome.
A1C>8.5 in first trimester assoc with what congenital malformations (NTD); not true of GDM since hyperglycemia is not seen in the first trimester
labor mgmt in diabetic patient target del at 40wks, induce if <4500g (check L/S>2.5), sch C section if >4500g; use insulin drip intrapartum and off after del. use ISS
fetal problems with diabetic mother hypoglycemia, hypocalcemia, polycythmia, hyper bili, RDS
european preg patient with twins, has intractable puritis worse at night on palms and soles and elevated Bili intrahepatic cholestasis in preg (tx is ursodeoxycholic acid)
acute fatty liver in pregnancy due to fetus abn fat metabolism so you see HTN, proteinuria, edema, elevated LFTs, low BS, inc Bili, DIC, inc ammonia (tx with IVF and delivery)
tx asx bacturia in preg macrobid or amoxicillin or cefalexin
tx of pyelonephritis in preg IVF and IV cephalosporin or gentamicin and tocolysis
when can D and C be done for abortion before 13wks gestation
when can we use misoprostol for abortion used in the first 63 days of amenorrhea
second trimester methods of abortion D and E and partial birth
spontaneous birth occurs when <20wks adn <500g fetus true
fetal demise in utero death after 20wks, loss of fetal movements
half of preg complicated by threatened abortion go to term true, you need a speculum exam and check for doppler for fetal cardiac activity
pregnant woman with bleeding, painful cramps and dilated cervix on exam inevitable abortion
loss of early preg but no S/S, and no cardiac activity on US missed abortion
mgmt of incomplete abortion US confirms debris and you need to do a D/C
mgmt of complete abortion no debris on US check serial B HCG to be sure an ectopic was not missed
what is a complication that needs to be ruled out with fetal demise check coags to r/o DIC; if it's there then the baby needs to be delivered immediately
tx of ectopic preg if ruptured surgery if not can use MTX, give rhogam to RH neg woman, f/u BHCG to ensure complete removal of fetus
when do you use MTX in ectopic if <3.5cm, no fetal heart sounds, bHCG<6000, no hx of folic supplementation
what do you need to r/o before perform cerclage for cervical insuff r/o chorioaminionitis
tx of cervical insuff elective cerclage at 13-16wks with >3 unexplained midterm preg losses; remove it at 36-37wks gestation
short cervix on exam at 16 wks, but no symps or dilated cervix what do we do? monitor with US if short at 20wks
define IUGR EFW is <5-10% of gest age or <2500g; accurate dating needed and if <20wks and don't know age check US (later US not accurate)
review IUGR chart p. 406
define macrosomia EFW>90-95% of gestation age or birth wgt 4000-4500g
Diagnose PROM or ROM sterile vaginal exam seen posterior fornix pooling, nitrazine positive, ferning positive, US oligohydraminos
clinical dx of Chorioamnionitis maternal fever and uterine tenderness, confirmed ROM, abs of URI/UTI
what to do with PROM<24 wks gestation manage at home on bed rest
PROM mgmt at 24-33weeks hospitalize give IM betamethasone, cervical cx, ppx amoxicillin and erythromycin for 7 days
PROM mgmt at 34wks initiate delivery
review stage of labor p. 409
mgmt umbilical cord prolapse don't replace cord, place mom in knee to chest, elevate presenting part of cord and add tertbutaline to decrase force of contractions, preform immediate C section
changes in FHR on monitor are related to the following uterine hyperstim, fetal head compression, umbilical cord compression, placental insuff
nl FHR 110-160bpm
FHR tachy/ brady due to the following tachy (meds- beta agonist, terbutaline, ritodrine); brady (BB or local anesthetics)
Acceleration on monitor abrupt increase in FHR<2min and unrelated to contractions (reassure)
Early deceleration on monitor gradual dec in FHR begin and end with contraction due to fetal head compression
variable decleration on monitor abrupt dec in FHR unrelated to cxn; due to umbilical cord compression; indicate fetal acidosis (not reassure)
late deceleration on monitor gradual dec in FHR come delayed in relation to CXN; uteroplacental insuff, indicate fetal acidosis (bad)
variability on monitor 6-25BPM between and is reassuring
stepwise approach to nonreassuring fetal trace check strip, evaluate for drug causes; d/c meds, give IV fluid, high flow O2, put patient on her left, vaginal exam r/o prolapsed cord, scalp stim; prep for delivery if no improvement; if unclear get fetal scalp PH (need dilated cervix and ROM)
optimum time for external version for 37wks and success is 60-70%
breast feeding buys you 3 months off birthcontrol true
Diaphragm and IUD should no be placed for 6 wk after del true
combined birth control not used for 3wks post del to prevent dvt; not used if breast feeding due to decreased lactation
progesterone only can be used right after del true
review post partum fever chart p. 414
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