6372130
Description
Flashcards by Christian Cervan, updated more than 1 year ago
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Created by Christian Cervan
over 7 years ago
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| Question | Answer |
| Prostaglandins | 1. Generated from the breakdown of phospholipids and cell membranes 2. Thought to increase sensitivity to pain |
| Bradykinin | 1. Released from plasma that leaks from surrounding blood vessels at the site of tissue injury 2. Binds to receptors on peripheral nerves, increasing pain stimuli 3. Binds two cells that cause a chain reaction producing prostaglandins |
| Substance P | 1. Found in pain neurons of dorsal horn (excitatory peptide) 2. Needed to transmit pain impulses from periphery to higher brain centers. 3. Causes vasodilation and edema |
| Histamine | Produced by mast cells causing capillary dilation and increased capillary permeability |
| Serotonin | Released from the brainstem and dorsal horn to inhibit pain transmission |
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