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376151
Hanta virus
Description
Mind Map on Hanta virus, created by Paulina Morales on 11/21/2013.
Mind Map by
Paulina Morales
, updated more than 1 year ago
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Created by
Paulina Morales
about 11 years ago
63
1
0
Resource summary
Hanta virus
VIEJO MUNDO
VIRUS HANTAAN
FHSR
NUEVO MUNDO
VIRUS SIN NOMBRE
1° en 1993
SDRA
VIRUS ANDES
CHILE
SCPH
Reservorio
Oligoryzimis longicaudatus
enfermedad cronica silenciosa
Atacama - Aysen
ARN (3 segmentos), envuelto, SS
afecta mas a hombres, promedio 32 años
ingresa al cuerpo
replica en endotelio pulmonar, cardiaco, otros
MANIFESTACION CLINICA
EL
FIEBRE
CEFALEA
SINTOMAS GASTROINTESTINALES
SCPH
FASE PRODROMICA
FIEBRE ALTA, MIALGIAS, SINTOMAS GASTROINTESTINAL
TROMBOCITOPENIA
RTO. PQ < 150.000
VIRUS + INRTEGRINA B3
permeabilidad vascular
activacion PQ
afecta interaccion de PQ c/ endotelio y adhesion
Leucocitosis > 12.000
Desviacion izq
c/ o s/ G.P
VHS N o Aumentado
Aumenta agregacion celular
Hemoconcentracion
Aumento HTO > 50%
aumenta permeabilidad vascular
extravasacion plasma
Inmunoblastos
Linfoblastos c/ estimulacion Ag
Aumento relacion N/C
Nucleolo prominente
Citoplasma moderadamente hiperbaso
> 10% de linfocitos
INMUNOBLASTO
apoyo c/ Rx
FASE CARDIOPULMONAR
Edema y dificultad resp.
aumento linfo T y citoquinas
aumenta permeab. vascular y agreg. PQ
muerte
Convalescencia
Trombocitopenia
Rto. PQ < 100.000
Hemoconcentracion
Leucocitosis > 25.000
Desv. izq y linfo inmaduros
Hipoprotrombiemia
aumento LDH. TTPKA. CPK
FASE CONVALESCENCIA
Sospecha de hantavirus
sintomas fisicos
Trombocitopenia
Rx c/ infiltrados
Exposicion a situacion de riesgo
SDRA
Muerte x cuadro resp. inexplicable + edema pulmonar
Confirmacion Dx
recoleccion y envio de muestra
ISP
NOTIFICAR SERMEMI DE SALUD
Serologia
ELISA IgM o IgG
ISP y UACH
TR-PCR
Fase aguda
ISP
IHQ
CDC Atlanta
UACH
Necropsia
Screening
UACH
IX, XIV y X
ELISA
SEREMI
TR.PCR
Tratamiento
SCPH LEVE
SCPH GRAVE
Media attachments
INMUNOBLASTO (image/jpg)
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