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3. Inflammation

inflammation
1. deals with infected organisms where they have entered the body
2. sends out disttress signals to WBC's to come to the scene
3. redness-due to vasodilation of blood vessels in the infected area to increase blood flow
4. heat - result of increased blood flow
5. swelling - extra blood forces fluid into the damaged tissues - allows immune cells from blood to get to site of infection
6. pain - swollen tissues press on nerves
innate immunity is NOT only physical defenses
inflammation triggered by damaged cells
1. phagocytes accumalate to increase rate at which bacteria and debris can be dealt with by phagocytosis
2. ruptured local cells, mast cells and basophills release alarm chemicals such as histamines and kinins
  1. causes vasodilation
    1. leads to signs of inflammation
  2. attract other cells from blood to the area
early inflammation and phagocytosis are non-specific
1. used against any invading pathogen
  1. sometimes this is all the response that is needed
  2. sometimes these responses keep infection under control until specific adaptive immunity has been tailor made to that specific pathogen
3.1.2
1. when a pathogen enters millions of cells try to defend
2. bacteria, viruses and fungi are prevalent in environment
  1. most are not harmful
  2. some can quickly and aggressively invade given the chance
    1. small cuts/pricks easily become septic
      1. some symptoms due to bacteria causing damage
      2. some symptoms are due to immune response

3. Inflammation

	Created by sajedashah over 10 years ago