Serotonin: One of the best researched
neurotransmitters, it is involved in emotion, sleep,
and mental well being.
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Now why was this? Testing determined that there were increased level of serotonin, specifically in the
Hypothalamus and Frontal Cortex. It can be concluded that sensory deprivation triggered this
release of serotonin.
Study on how sleep deprivation affects the brain in regards to neurotransmission,
looking specifically at serotonin.
Kasamatsu & Hirai (1999)
The Target Population was a group of Monks on a 72 hour pilgrimage to a mountain.
The Monks were not allowed to speak, eat or drink, they were exposed to cold late
autumn weather, after 48 hours, the Monks started seeing hallucinations of
ancestors and feeling their presence.
This study is a prime example of how human behavior is effected by neurotransmission, in this case being the difference in serotonin levels causing hallucinations.
These hallucinations can account for different behaviors in humans due to the fact that when
hallucinating, external stimulus is being given to the brain but reality is distorted, hallucinations being
sensations that appear real but are created by your mind can make people act irrationally, talk to
inanimate things, become paranoid along with many other symptoms.
Thesis: Neurtransmission is the reason we behave how we behave, affecting emotions, pain
perception, memory, perception of reality and many other things.
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Must be understood
that different
neurotransmitters
affect the body and
brain differently,
resulting in the
variation of effects
produced by
neurotransmission.
Neurotransmission:
the transmission of
nerve impulses
across a synapse.
Dopamine is involved in movement, memory, pleasurable reward behavior, cognition attention as well as others things
Stydy: Hietala 1996
This lead to the conclusion that it was indeed a change in dopamine levels which caused schizophrenia;
a psychotic disorder marked by severely impaired thinking,
emotions, and behaviors.
Other studies have supported this and have lead to the conclusion that schizophrenia is directly related to abnormally high levels of dopamine.
This means that schizophrenic behavior is most often in concurrence with elevated dopamine levels and excess neurotransmission in this case by dopamine can cause psychotic behavior.
Uptake of flurodopa, a radioactive compound was measured and scanned by a PET scan for 7
schizophrenic patients and 8 healthy people. The fluorodopa influx constant increased in
schizophrenic patients. Alterations in presynaptic dopamine function make people more inclined to
have schizophrenia compared to the control group.