First Generation Nonsteroidal
Antiinflammatory Drugs (NSAIDs)
Action: Suppress inflammation by inhibiting both
cyclooxygenases 1 & 2, enzymes that are responsible
for the synthesis of prostaglandins. NSAIDs inhibit the
formation and release of prostaglandin. (Blocks the Cox enzyme)
Treats: rheumatoid arthritis,
osteoarthritis, inflammation,
pain, headache and fever.
Common
side
effects:
Nausea
Upset
Stomach
Avoid alcohol and ASA
Monitor: Pain
Take with food or milk
Generic & Trade Names: Ibuprofen (Advil, Motrin)
Opioids
Actions: Binds with receptors in the brain and spinal
cord that are associated with pain. operate opioid
analgesics are similar to morphine however the pain
control is less effective, and potential for respiratory
depression is less.
Common
side effects:
dry mouth
stomach pain
drowsiness
nausea
Action: SSRIs decrease the reuptake of
serotonin at selected nerve terminals in the
CNS and increase serotonin activity at the
nerve synapse. Increased availability of
serotonin at the receptors results in mood
elevation and reduced anxiety
Treats: Major Depression,
OCD, and Anxiety
Puts patient at increased risk of suicide
Common
Side Effects:
Headache
Nausea
Lethargy
Fatigue
Insomnia
Sexual
Dysfunction
Weight Gain
General &
Trade Names:
Fluoxetine
(Prozac)
Cholinesterase inhibitor (Alzheimer's Disease)
Used to slow progression of dementia symptoms
Common
Side Effects:
Nausea
Vomiting
Dyspepsia (Indigestion)
Diarrhea
Generic & Trade
Names: Donepezil
(Aricept)
Action: Enhances cholinergic transmisson in the brain.
Monitor: Pulse
Dorzolamide (Trusopt)
Action: Reduces the amount of fluid in the eye.
Check eyes for contacts
Common Side Effects: Nausea, Dry/Watery eyes, Headache
Treats: Open-Angle Glaucoma
Analgesics
Action: Inhibits the synthesis
of prostaglandins that may
serve as mediators of pain
and fever.
Monitor: Pain
Common
Side
Effects:
fatigue,
anxiety,
vomiting,
nausea