A MAB works by recognising and
finding specific proteins on cells.
Some work on cancer cells,
others target proteins on cells
of the immune system.
Some MABs attach themselves to cancer
cells, making it easier for the cells of the
immune system to find them.
Other MABs work by acting on cells of the
immune system. For example,
immunotherapies called checkpoint inhibitors
block proteins that stop the immune system
attacking cancer cells.
Side affects
Allergic reaction during
treatment
skin changes such as red and sore
skin or an itchy rash
diarrhoea, tiredness, flu-like
symptoms such as chills, fever,
dizziness
Websites used
Cytokines
Cytokines are a group of proteins in the
body that play an important part in
boosting the immune system.
There a two main types
interferon and aldesleukin
interferon as an injection
just under the skin
Most people have interferon 3
times a week. Or you might have it
as a daily injection.
Aldesleukin is most often used to treat
kidney cancer. It is also in clinical trials for
some other types of cancer.
Adoptive cell transfer
This type of immunotherapy is still quite
new. So still be tested
For CAR T-cell therapy, the machine
takes out your T cells.
In the lab, they change the T cells. This is
now a CAR T cell
The aim is for the CAR T-cells to then
recognise and attack the cancer cells.
This is still in the trial phase at
the moment. But it has been
tested for leukaemia