Cardiac Drugs

Description

Mind Map on Cardiac Drugs, created by aliswright on 10/08/2013.
aliswright
Mind Map by aliswright, updated more than 1 year ago
aliswright
Created by aliswright over 11 years ago
39
1

Resource summary

Cardiac Drugs
  1. Thiazide diuretics
    1. First line treatment
      1. Stops body from selectively reabsorbing sodium circulating blood volume decreased
        1. Bendroflumethiazide
          1. Contraindication = gout as increases uric acid Potassium depletion
          2. Nitrates
            1. Rapid relief - GTN Prophalaxis - isosorbide mononitrate
              1. Angina
                1. Vasodilator, decreased preload and afterload
                  1. Unwanted effects - postural hypotension, flushing, headache
                    1. Given - sublingual, buccal (instant) Patch, capsule
                    2. Calcium channel blockers
                      1. Calcium = smooth muscle contraction, vasodilator, decreased afterload, HR and contractility
                        1. Angina (prophalaxis) Hypertension
                          1. Headache, flushing, oedema, fatigue, palpitations
                            1. Myocardium action - verapamil Blood vessel action - amlodipine
                              1. PINE
                              2. Beta blockers (antagonists)
                                1. Hypertension
                                  1. B1 (cardiac) receptors, SNS
                                    1. Angina, post MI, hypertension, chronic HF, anxiety...
                                      1. Unwanted effects - Bronchoconstriction in asthma, HF
                                        1. LOL
                                        2. ACE (angiotensin-converting enzyme) inhibitors
                                          1. Stop angiotensin 2, a vasoconstrictor, from acting on the blood vessels - stops the conversion of angiotensin 1 - 2.
                                            1. Unwanted effects - Hypotension, dry cough (irritated bronchial mucosa)
                                              1. PRIL
                                                1. Catopril (more side effects), lisinopril, ramipril
                                                2. Angiotensin 2 receptor antagonists
                                                  1. Vasodilator - Block angiotensin 2 receptors preventing vasocontriction
                                                    1. Used when patients cannot take ACE inhibitors
                                                      1. ARTAN
                                                        1. Candesartan, losartan,eprosartan
                                                        2. Digitalis drugs - digoxin
                                                          1. Increases force of cardiac contraction and lowers HR
                                                            1. AF and HF
                                                              1. Not is HR is below 60
                                                              2. Alpha adrenoreceptor antagonists
                                                                1. Block A1 receptors of SNS = vasodilation
                                                                  1. Hypertension, cardiac failure
                                                                    1. Unwanted effects - Dizzyness, hypotension, tachycardia
                                                                      1. SIN/IN
                                                                      2. Atropine
                                                                        1. Antimuscarinic - blocks acetocholine receptor in PNS
                                                                          1. Used in bradycardia (eg, after MI)
                                                                          2. Statins
                                                                            1. Lower cholesterol - inhibit enzyme in liver needed for cholesterol synthesis
                                                                              1. Atorvastatin, simvastatin
                                                                              2. NICE guidelines for treatment of hypertension
                                                                                1. A = ACE inhibitor C = calcium channel blocker D = diuretic (eg, thiazide)
                                                                                  1. Step 1 = A or C (if 55+ or black)
                                                                                    1. Step 2 = A + C
                                                                                      1. Step 3 = A + C + D
                                                                                        1. Step 4 = A + C + D + diutetic, alpha blocker or beta-blocker
                                                                                        Show full summary Hide full summary

                                                                                        Similar

                                                                                        Cardiac Drugs
                                                                                        Megan Daniel
                                                                                        Pharmacology Term 2
                                                                                        Marielle83
                                                                                        A-Level Biology: Cell Division
                                                                                        cian.buckley+1
                                                                                        The Great Gatsby: Chapter Summaries
                                                                                        Andrew_Ellinas
                                                                                        P2a revision (part 1)
                                                                                        juliasutton
                                                                                        GCSE Computing - 4 - Representation of data in computer systems
                                                                                        lilymate
                                                                                        Who was to blame for the Cold War?
                                                                                        Will Barnes
                                                                                        Geography AQA Revison topics Migration, Population Change, Youthful Populations and more
                                                                                        dburns8731
                                                                                        Geography: Population
                                                                                        ameliaalice
                                                                                        Cell Transport
                                                                                        Elena Cade
                                                                                        Simple Present Tense (Test)
                                                                                        Onur Kalafat