2645047
Description
Mind Map by Fern Chipperfield, updated more than 1 year ago
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Created by Fern Chipperfield
almost 11 years ago
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Gluconeogenesis
- Function
- To form Glucose from non-carbohydrate sources when thier isnt enough carbohydrate available
- Takes place in: 90% in the liver and 10% in the kidneys
- Uses ATP
- To form Glucose from non-carbohydrate sources when thier isnt enough carbohydrate available
- Starting Material
- LACTATE in Muscle, travels to the liver to be broken down into pyruvate, then goes though gluconeogenesis
- GLYCEROL from break down of fats from beta-oxidiation
- NOT FATTY ACIDS
- LACTATE in Muscle, travels to the liver to be broken down into pyruvate, then goes though gluconeogenesis
- PYRUVATE: combines with CO2 +ATP+ H2O = OXALOACETATE + ADP +Pi + 2H+
- OXALOACETATE is reduced to MALATE by MALATE DEHYDROGENASE and NADH + H+ to get though to the cytosol
- MALATE is then OXIDISED back to OXALOACETATE by NAD+
- OXALOACETATE combines with GTP = Phosphophenolpyruvate using the enzyme PHOSPHOPHENOLPYRUVATE CARBOXYKINASE
- PYRUVATE goes in via PHOSPHOPHENOL PYRUVATE
- PYRUVATE goes in via PHOSPHOPHENOL PYRUVATE
- OXALOACETATE combines with GTP = Phosphophenolpyruvate using the enzyme PHOSPHOPHENOLPYRUVATE CARBOXYKINASE
- MALATE is then OXIDISED back to OXALOACETATE by NAD+
- OXALOACETATE is reduced to MALATE by MALATE DEHYDROGENASE and NADH + H+ to get though to the cytosol
- GLYCEROL
- GLYCEROL froms GLYCEROL PHOSPHATE using the enzyme GLYCEROL KINASE
- GLYCEROL KINASE then forms DIHYDROXYACETONE PHOSPHATE byt GLYCEROL PHOSPHATE DEHYDROGENASE
- GLYCEROL goes into DIHYDROXYACETONE PHOSPHATE
- GLYCEROL goes into DIHYDROXYACETONE PHOSPHATE
- GLYCEROL KINASE then forms DIHYDROXYACETONE PHOSPHATE byt GLYCEROL PHOSPHATE DEHYDROGENASE
- GLYCEROL froms GLYCEROL PHOSPHATE using the enzyme GLYCEROL KINASE
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