inhaled air in the alveolar has a
high pO2 than in the rest of the
tissues, and blood in the lungs has alower pO2.
this results in a diffusion gradient
and this causes oxygen to move
from the alveoli into the
haemoglobin in blood cells till the
blood is loaded with oxygen.the
heamoglobin is now called
oxyhaemoglobin as it now has more
oxygen.
the oxygenated blood is then taken to
tissues where the cellls are respiring all the
time and have a low pO2. so because the
blood has a high pO2, oxygen will diffuse
into the tissues and then get used for
respiration.
the blood is then left with a lower
partial pressure of oxygen
how hydrogen carbonate ions are formed
Carbon dioxide diffuses into red
blood cells some of the carbon
dioxide will combine with amino acids
to form carbine-haemoglobin.
Carbon-hydrase in the red blood cell will catalyse the
reaction betwwen water and carbon dioxide to form
carbonic-acid
Carbonic acid dissociates into negatively charged
hydrogen carbonate and positive hydorgeb ions.The
hydrogen ions increase the acidity of blood and
combine with Hb to give haemoglobin blood.This
decreases the affinity of HB to oxygen and gives it
up to the tissues resulting the Bohr effect .
Releasing oxygen the Bohr effect
The high
concentration of
carbon dioxide
causes events in the
erythrocyte that
make the
haemoglobin release
some oxygen
This is called the Bohr effect
named after Christian Bohr in
1904
high
concetrations of
carbon dioxide
are found in
respiring tissues
which need
oxygen.
These High carbon dioxide
concetrations cause
haemoglobin to relaease its
oxygen even more readily than it
would otherwise do.
When a dissociation curve is
drawn for haemoglobin at
high concetrations of carbon
dioxide the curve will lie to
the right of and below the
standard curve.
Therefore it can be seen as a high carbon
dioxide concetration lowers the affinity of
haemoglobin for oxygen.
How carbon dioxide is transported
Carbon dioxide is produced from respiring tissue
it transported in the blood and to the lungs
whereby it i released out of the body.
5% of carbon dioxide will disolve into
the plasma.Some of the carbon dioxide
diffused into the erythrocytes called
Carbonic anyhydrase
10% is combined directly with haemoglobin to
form the compound carbaminohaemoglobin.This
is oxygen that has not been brought to carbonic
anhydrase attention so instead it combine directly
with haemoglobin.
85% is tranported in the form hydrogen carbonate
Carbon dioxide+water +Carbonic acidb because of the Carbonic anhydrase
enzyme which catalye the reaction.Carbonic acid then splits as a result a
hydrogen ion is formed plus hydrogen carbonate ion