5326063
Description
Mind Map by Jess Hughes, updated more than 1 year ago
|
Created by Jess Hughes
almost 8 years ago
|
|
Biological approach to explaining
OCD (GENETIC)
- COMT gene
- Involved in production
of catechol - O
-methyltransferase
- Regulates production
of neurotransmitter -
DOPAMINE
- One allele of the
gene has been
found to be more
abundant in those
with OCD
- This allele produces
lower activity of COMT
gene and higher levels
of dopamine
- This allele produces
lower activity of COMT
gene and higher levels
of dopamine
- Involved in production
of catechol - O
-methyltransferase
- SERT gene
- Affects transport of
SEROTONIN, creating
lower levels of the
neurotransmitter
- One study found a
mutation of the gene
in 2 unrelated
families and 6/7 had
OCD
- Affects transport of
SEROTONIN, creating
lower levels of the
neurotransmitter
- DIATHESIS - STRESS
- Each individual gene ONLY
creates a vulnerability
(diathesis) for OCD as well
as other conditons, i.e.
depression and PTSD
- Other factors
(stressors) affect
what condition
develops
- So someone could have
the COMT and SERT
genes but no ill effects
- Each individual gene ONLY
creates a vulnerability
(diathesis) for OCD as well
as other conditons, i.e.
depression and PTSD
- Family and twin studies
- 80 patients with OCD and 343 of
their first degree relatives were
compared to 73 people without
mental illness and 300 of their
first degree relatives
- Found people with a first
degree relative with OCD
have a 5X greater chance
of having the illness at
some point.
- Found people with a first
degree relative with OCD
have a 5X greater chance
of having the illness at
some point.
- Meta analysis of 14 twin
studies found on average
MZ twins were over 2X
likely to develop OCD if 1
twin had the disorder
- 80 patients with OCD and 343 of
their first degree relatives were
compared to 73 people without
mental illness and 300 of their
first degree relatives
Want to create your own Mind Maps for free with GoConqr? Learn more.