8819675
Description
Mind Map by yasmin alkhatib, updated more than 1 year ago
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Created by yasmin alkhatib
almost 7 years ago
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muhammed's spleen
is palpable
- spleen
- cuases of splenomegaly
- primary or metastatic neoplasm
- leukemia
- lymphoma
- carcinoma
- sarcoma
- leukemia
- hemolytic anemias
- immunologicinflammatory disorders
- lupus
- sarcoidosis
- amyloidosis
- lupus
- storage diseases
- gaucher
- neimann pick
- gaucher
- splenic vein hypertension
- cirrhosis
- cirrhosis
- complications
- spleen infarction
- frequent infections &easy bleeding
- anemia
- fulleness
- spleen infarction
- grades
- primary or metastatic neoplasm
- upper left quadrant of the abdomen
- histology
- stroma
- capsule
- trabeculae
- reticular network
- capsule
- parenchyma
- white pulp
- red pulp
- white pulp
- stroma
- physical examination
- supine position
- supine position
- cuases of splenomegaly
- who can donate blood
- aged between 17 and 66
- weight over 50kg
- doesn't have diseases like
- high blood pressure
- diabetes
- anemia
- high blood pressure
- aged between 17 and 66
- WBC's
- disorders
- neoplastic
- myeloid
- Acute myeloid leukemia
- Age 15-60
- >20% blast cells in BM and blood
- Auer bodies
- Age 15-60
- chronic myeloproliferative disorder
- JAK2 mutations
- essential thrombocythemia
- myelofibrosis
- Polycythemia vera
- essential thrombocythemia
- BCR-ABL
t(9:22)
- chronic myeloid leukemia
- Age 40-60+
- decreased LAP
- stages
- chronic phase
- Accelerated phase
- Blast phase
- chronic phase
- treatment
- stem cell transplants
- imatinib
- tyrosin kinase inhibitor
- tyrosin kinase inhibitor
- stem cell transplants
- risk factors
- ionizing radiation in high doses
- ionizing radiation in high doses
- epidemiology
- slow progression
- pathophysiology
- Age 40-60+
- chronic myeloid leukemia
- JAK2 mutations
- Acute myeloid leukemia
- lymphoid
- non hodgkin's lymphoma
- multiple myeloma
- Hodgkin's lymphoma
- chronic lymphocytic leukemia
- Age 60+
- proliferation of neoplastic lymphoid cells (B cells)
- sumdge cells
- Age 60+
- Acute lymphoblastic leukemia
- Age <15
- composed of pre B or pre T lymphocytes
- +TDT test
- Age <15
- non hodgkin's lymphoma
- histiocytic
- myeloid
- non neoplastic
- reactive leukomoid reaction
- excessive leucocytosis that may mimic leukemia
- 15000-100,000 cells/µL
- elevated NAP
- presence of cytoplasmic toxic granulation
- excessive leucocytosis that may mimic leukemia
- related diseases
- reactive leukomoid reaction
- neoplastic
- disorders
- investigations
- CBC
- blood smear
- normal
- normal
- genetic test
- conventional cytogenetics
- PCR
- FISH
- conventional cytogenetics
- BM biopsy or aspiration
- CBC
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