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Antimicrobials (Unfinished)

Description

An antimicrobial tree that begins with the various classes of antimicrobial therapy and ends with specific drugs and their uses
Breanna Felldin
Mind Map by Breanna Felldin, updated more than 1 year ago
Breanna Felldin
Created by Breanna Felldin over 6 years ago
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Resource summary

Antimicrobials (Unfinished)
  1. Cell Wall Synthesis Agents
    1. Beta-Lactams
      1. Cephalosporins
        1. 1st Generation
          1. Cephalexin (PO)
            1. Cefazolin (IV)
              1. Treats
                1. Gram positive aerobes
                  1. Ideal for Streptococci and MSSA
              2. 2nd Generation
                1. Cefuroxime (IV, PO)
                  1. Cefaclor (PO)
                    1. Cephamycins
                      1. Cefotetan IIV)
                        1. Cefoxitin (IV)
                          1. Only cephalosporins that treat Bacteroides (gut anaerobe)
                        2. 3rd Generation
                          1. Cefdinir (PO)
                            1. Cefpodoxime (PO)
                              1. Ceftriaxone (IV)
                                1. Ceftazidime (IV)
                                  1. Pseudomonas aeruginosa (gram negative aerobe)
                                  2. Cefotaxime (IV)
                                  3. 4th Generation
                                    1. Cefepime (IV)
                                      1. Pseudomonas aeruginosa
                                    2. 5th Generation
                                      1. Cefaroline (IV)
                                        1. MRSA
                                      2. Gram negative activity increases with higher generations
                                        1. All but Ceftazidime treat Streptococcus pneumoniae (gram positive aerobe)
                                        2. Penicillins
                                          1. Natural Penicillins
                                            1. Penicillin G (IV)
                                              1. Penicillin V (PO)
                                                1. Treats
                                                  1. Gram positive aerobes
                                                    1. Streptococci, Enterococci
                                                    2. Anaerobes
                                                      1. Mouth anaerobes like Peptostreptococcus, Actinomyces
                                                      2. Syphilis (DoC)
                                                    3. Penicillinase-Resistant Penicillins
                                                      1. Oxacillin (IV)
                                                        1. Nafcillin (IV)
                                                          1. Dicloxacillin (PO)
                                                            1. Treats
                                                              1. Gram positive aerobes
                                                                1. Streptococci, Staphylococci (MSSA)
                                                                2. MSSA better than vancomycin
                                                              2. Aminopenicillins
                                                                1. Ampicillin
                                                                  1. DoC for Listeria
                                                                  2. Amoxicillin
                                                                    1. Treats
                                                                      1. Gram positive aerobes
                                                                        1. Streptococci, Enterococci, Listeria
                                                                        2. Gram negative aerobes
                                                                          1. E. coli, Haemophilus, Proteus
                                                                      2. Antipseudomonal Penicillins
                                                                        1. Ticarcillin
                                                                          1. Piperacillin
                                                                          2. Extended Spectrum Penicillins/Beta-Lactamase Inhibitor Combinations
                                                                            1. Ampicillin/Sulbactam (IV)
                                                                              1. Actinobacter (hospital bug)
                                                                              2. Amoxicillin/Clavulanate (PO)
                                                                                1. Piperacillin/Tazobactam (IV)
                                                                                  1. Pseudomonas, Enterobacter, Serratia, Morganella, Citrobacter
                                                                                  2. Treats
                                                                                    1. Gram positive aerobes
                                                                                      1. Parent drug + MSSA
                                                                                      2. Gram negative aerobes
                                                                                        1. E. Coli, Klebsilla, Proteus, Haemophilus
                                                                                        2. Anaerobes
                                                                                          1. Mouth anaerobes like Fusobacterium, Prevotella, Bacteroides, & gut anaerobes like Bacteroides
                                                                                    2. Carbapenems
                                                                                      1. Imipenem
                                                                                        1. Meropenem
                                                                                          1. Ertapenem
                                                                                            1. Doripenem
                                                                                          2. Monobactams
                                                                                            1. Aztreonam
                                                                                            2. Lipoglycopeptides
                                                                                              1. Telavancin
                                                                                                1. Dalbavancin
                                                                                                  1. Oritavancin
                                                                                                  2. Glycopeptides
                                                                                                    1. Vancomycin
                                                                                                      1. Bacitracin
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