63 year old woman presents after falling down some stairs and is found to have a small subarachnoid haemorrhage. Initial FBC normal. As she is on aspirin for coronary artery disease the neurosurgery team orders a platelet transfusion. She recovers an is sent home. One week later she returns with severe bruising and epistaxis. Platelet count is 8× 109/L, normal Hb and WCC. What is likely to be found in the history of the patient or the donor of the apheresis platelet unit?
Patient has a history of previous anaphylactic reaction to transfusion
Donor has a history of previous anaphylactic reaction to transfusion
Patient has a history of previous pregnancies
Donor has a history of previous pregnancies
Patient has history of previous heparin induced thrombocytopenia
Donor has a history of previous heparin induced thrombocytopenia
Which of the following are correct: tick all correct answers
The Therapeutic Goods Administration (TGA) is the international regulatory agency for therapeutic goods.
The National Blood Authority (NBA) manages and coordinates arrangements for the supply of blood and blood products within Australia.
The Jurisdictional Blood Committee which oversees the NBA role includes membership of a number of the States and Territories.
National Pathology Accreditation Advisory Committee advises health ministers on matters relating to the accreditation of pathology laboratories.
Transfusion of 1 unit of platelets prepared from one whole blood donation into an average sized adult with no active bleeding, splenomegaly or history of transfusion or pregnancy is anticipated to increase the platelet count by:
1–5 × 109/l
3–5 × 109/l
5–10 × 109/l
20–40 × 109/l