What is therapeutic drug monitoring (TDM)?
What do we mean by therapeutic range?
What does it mean if a drug has a narrow therapeutic index?
What makes a drug a good candidate for therapeutic drug monitoring?
what are some factors that can cause variability in pharmacokinetcs
How do we determine the therapeutic range?
What are some assay techniques used to measure plasma/serum/blood concentrations?
Which of the assay techniques listed below use antibodies?
RIA, HPLC, FPIA, EMIT
What is a disadvantage of an assay that uses antibodies?
What are advantages and disadvantages of techniques such as RIA, FPIA and EMIT compared to HPLC?
Why should an assay be validated and how do we do this?
When you have a result for a patient from TDM, what factors do you need to consider when interpreting the result?