When the ligand has bound, what moleucle forms?
A heterodimer within the T.K family
A heterotrimer within the T.K family
What is found in the active site that inhibits activity?
An activation lip
A hydrophobic core that must be exposed
How do you activate the active site?
Which residues of tyrosine kinase are modified?
What domain is required to bind to an activated Tyrosine Kinase?
How large is an SH2 domain?
How many pockets are there in SH2?
How does a specific molecule know where to dock on a tyrosine kinase receptor?
The sequence of aa around the modification it binds to
The shape of the protein around the modification it binds to