Enzyme Regulation - Macromolecular Inhibition

Question 1 of 9

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Choose the correct macromolecular inhibitor involved in enzyme regulation?

Select one of the following:

  • Protease Inhibitors

  • Elastase Inhibitors

  • Amylase Inhibitors

Question 2 of 9

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Where do Serpins reside in the body?

Select one of the following:

  • Lymph

  • Blood

  • Brain

Question 3 of 9

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What processes are Serpins involved in?

Select one of the following:

  • Growth and Development

  • Coagulation and Inflammation

  • Cellular Differentiation

Question 4 of 9

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What type of complex do Serpins form with target Proteases?

Select one of the following:

  • Ionic Complex

  • Hydrophobic Complex

  • Covalent Complex

Question 5 of 9

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What type of conformational change do Serpins undergo?

Select one of the following:

  • Stressed to Relaxed transition

  • Breaking of Covalent Bonds

  • Hydrogen Bond formation

Question 6 of 9

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What type of bond is formed between the Enzyme-Substrate complex following nucleophilic attack of Serine on the peptide bond of the substrate?

Select one of the following:

  • Hydrogen Bond

  • Ester Bond

  • Covalent Bond

Question 7 of 9

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What is formed following ester bond formation on the substrate-enzyme complex?

Select one of the following:

  • Acyl Enzyme Intermediate

  • Enzyme-Substrate Complex

  • Serpin-Protease complex

Question 8 of 9

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Hydrolysis of the acyl enzyme intermediate occurs at a __________ rate?

Select one of the following:

  • Fast

  • Slow

Question 9 of 9

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What happens when the serpin is attached to the protease?

Select one of the following:

  • The Serpin is Consumed

  • The Serpin is Reused

  • The Serpin is Hydrolysed

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Enzyme Regulation - Macromolecular Inhibition

daniel.praecox
Quiz by , created almost 3 years ago

This quiz assess the knowledged examined in the notes on regulation of enzyme activity by macromolecular inhibition.

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jill.examtime
Created by jill.examtime almost 3 years ago
daniel.praecox
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