Macrocytic Anaemia

Question 1 of 24

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What defines Non-Megaloblastic Anaemia?

Select one of the following:

  • No large nucleus & excess cell membrane- no DNA involvement

  • Large nucleus, effected DNA

Question 2 of 24

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In Melagoblasic Anaemia, other blood cells are likely to be affected

Select one of the following:

  • True
  • False

Question 3 of 24

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Liver disease and alcohol cause what type of anaemia?p

Select one of the following:

  • Melagoblastic Macrocytic

  • Non-Megaloblastic Macrocytic

Question 4 of 24

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Which of the following is not a cause of Melagoblastic Anaemia?

Select one of the following:

  • HIV treatment

  • B12 deficiency

  • Iron deficiency

  • Folate deficiency

Question 5 of 24

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Pancytopaenia- a reduction of all three blood components

Select one of the following:

  • True
  • False

Question 6 of 24

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Why is pancytopaenia a symptom of Megaloblastic anaemia?

Select one of the following:

  • Cells apoptose due to DNA synthesis failure

  • Cells cannot be produced due to crowded bone marrow

  • Cells die because of insufficient folate

Question 7 of 24

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Megaloblastic anaemia leads to a shorter cell lifespan

Select one of the following:

  • True
  • False

Question 8 of 24

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Megaloblastic anaemia has an Inc MCV but Dec RDW

Select one of the following:

  • True
  • False

Question 9 of 24

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Erythrocyte precursors with retarded nuclear maturation

Select one of the following:

  • Megaloblasts

  • Oval Macrocytes

  • RBC fragments

Question 10 of 24

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Oval macrocytes -> larger reiculocytes ->

Select one of the following:

  • Larger R.B.C's

  • Smaller R.B.C's

  • Fragmented R.B.C's

Question 11 of 24

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In M.M.A, cells are less fragile and cannot be broken down, so they accumulate in the blood

Select one of the following:

  • True
  • False

Question 12 of 24

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Which of the following are symptoms of M.M.A?

Select one or more of the following:

  • Hypersegmented neutrophils

  • Giant Metamelanocytes

Question 13 of 24

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Which of the following are results of EXTREME B12/Folate deficiency?

Select one or more of the following:

  • Dementia

  • Neuropathy

  • Jaundice

Question 14 of 24

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What is the role of B12?

Select one of the following:

  • A Co-Enzyme

  • A substrate for globin production

  • A neurotransmitter

Question 15 of 24

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B12 is only synthesised in micro-organisms

Select one of the following:

  • True
  • False

Question 16 of 24

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Where is B12 stored?

Select one of the following:

  • The liver

  • The kidneys

  • The spleen

Question 17 of 24

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GI diseases, tapeworm and a lack of intrinsic factor all cause what?

Select one of the following:

  • Malapsorption of B12

  • Failure of B12 metabolism

  • Transcabalmin II deficiency

Question 18 of 24

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Transcabalmin II (TCII) deficiency can be tested for

Select one of the following:

  • True
  • False

Question 19 of 24

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Folate is very sensitive to cooking and will degrade easily

Select one of the following:

  • True
  • False

Question 20 of 24

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How long will the liver stores of folate last?

Select one of the following:

  • 3 weeks

  • 3 months

  • 3 years

Question 21 of 24

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Pregnancy and chronic haemolytic conditions cause what?

Select one of the following:

  • Inc Folate requirement

  • Inadequate folate intake

  • Folate malabsorption

Question 22 of 24

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Folate deficiency can be drug induced

Select one of the following:

  • True
  • False

Question 23 of 24

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Folate is vital for rapidly dividing cells

Select one of the following:

  • True
  • False

Question 24 of 24

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Folate deficiency can cause....

Select one of the following:

  • Spinal cord degeneration

  • Abnormal skin development

  • Everything starts tasting of fish

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Macrocytic Anaemia

gina_evans0312
Quiz by , created almost 3 years ago

Haematology and Anatomy (Red Blood Cells) Quiz on Macrocytic Anaemia, created by gina_evans0312 on 08/01/2014.

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Created by gina_evans0312 almost 3 years ago
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