What is MHC?
Presents antigens to T-cell on antigen presenting cells
Receives antigens from T-cells to antigen presenting cells
TCR's- T Cell Receptors that detect antigens presented by antigen presenting cells
Presentation of antigens through MCH/TCR activates the T-cell
How to Superantigens work?
Increase the presentation of antigens by MHC, super-stimulating the T-cells
Allows MHC/TCR binding without antigen present, super-stimulating the T-cells
Prevents T cell activation by destroying TCR's
Why are Superantigens dangerous
They prevent T-Cell activation
The over-activate T-Cells
Which causes T-Cells to over-release cytokins, causing shock like symptoms
Exotoxins are secreted during cell lysis
Which of the following are capable of producing Endotoxins?
What happens to exotoxins?
They're secreted during cell lysis
They secreted during normal cell function
They're expressed on the cell surface
Exotoxins tend to be produced by Gram +ve bacteria