Each islet contains 3000-5000 cells
How are glucose levels monitored?
High blood flow around cells
Insulin receptors on Beta cell surface
Flow of glucose in interstitial fluid
What is the role of the delta cells?
The Islets of Langerhans are only stimulated by the SNS
What is the role of glucagon?
To signal 'hunger'
To signal 'satiation'
To signal high blood flow
First Pre-proglucagon is converted into Proglucagon
In the small intestine, what is made from Proglucagon?
Glp1 & 2
Major Preglucagon Fragment
In the Alpha cells, what is made from Proglucagon?
Major Proglucagon Fragment
What controls glucagon secretion?
The nervous system
Glucose is a potent inhibitor of glucagon secretion
Amino acids and free fatty acids in the blood _ secretion
Why does glucagon have no effect on skeletal muscle?
So the muscles don't get depleted of glucose
So the muscles cannot take glucose from the blood
Glucagon stimulates insulin release
Which of the following is not a role of glucagon?
Mobilisation of liver glucose
Breakdown of TAGs to F.As
Inc protein synthesis
Inc cardiac contractility
Why does glucagon leads to the P of pyruvate kinase?
Reduce glycolysis & inc gluconeogenesis
Increase glycolysis & red gluconeogenesis
Stimulating pyruvate carboxylase stimulates glycolysis
Which of the following is deactivated in order to prevent lipogenesis
Acetyl CoA carboxylase
Phosphofructokinase 2 activates gluconeogenesis & inhibits glycolysis