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Year 2 Quiz on CD4 (T-Helper) Cell Polarisation, created by gina_evans0312 on 16/04/2014.

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gina_evans0312
Created by gina_evans0312 about 10 years ago
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CD4 (T-Helper) Cell Polarisation

Question 1 of 7

1

Th cells are activated by MHCII and a co-stimulation signal

Select one of the following:

  • True
  • False

Explanation

Question 2 of 7

1

CD4 T-cells are a major source of cytokines after activation

Select one of the following:

  • True
  • False

Explanation

Question 3 of 7

1

Which of the following is a major autokrine stimulator for clonal proliferation of Th cells?

Select one of the following:

  • IL2

  • IL3

  • IL4

Explanation

Question 4 of 7

1

Which of the following is not a factor in CD4 cell polarisation?

Select one or more of the following:

  • Infection type (I.e. does the microenvironment indicate a fungus, a virus?)

  • Amount of antigen/binding strength of antigen

  • 'Dose' of infection

Explanation

Question 5 of 7

1

Production of cytokines by one type of Th cell, causes the polaristion of native Th cells to the type that produced the cytokines (i.e. Th1 produced cytokines encourage Th1 conversion)

Select one of the following:

  • True
  • False

Explanation

Question 6 of 7

1

During non-infection, which cell is predominant?

Select one of the following:

  • Th1

  • Th2

  • Neither, till infection tips the balance

Explanation

Question 7 of 7

1

Name ways in which the activity of cytokines can be controlled

Select one or more of the following:

  • Short half life- only effect nearby cells

  • Specific receptors prevent unwanted signalling

  • High concentrations needed for cell activation

  • Active destruction by incorrect cells

Explanation