Acute Respiratory Distress Syndrome (ARDS)

Descrição

USMLE Step 2 Pulmonology (2e Respiratory Failure) FlashCards sobre Acute Respiratory Distress Syndrome (ARDS), criado por Aaron Samide em 24-05-2016.
Aaron Samide
FlashCards por Aaron Samide, atualizado more than 1 year ago
Aaron Samide
Criado por Aaron Samide quase 8 anos atrás
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Resumo de Recurso

Questão Responda
Primary mechanism of ARDS Diffuse inflammatory process due to neutrophil activation in systemic or pulmonary circulations
2012 Berlin criteria for ARDS (4) 1. Acute onset (<1 week) 2. Bilateral infiltrates on imaging 3. Pulmonary edema not otherwise explained 4. Abnormal PaO2/FiO2 ratio
Stratification of ARDS based on PaO2/FiO2 ratio (2012 Berlin definition) PaO2/FiO2 ratio: 200 to 300 = mild ARDS 100 to 200 = moderate <100 = severe
How do ARDS and cariogenic pulmonary edema differ in terms of cause? ARDS is caused by increased alveolar capillary permeability Cariogenic pulmonary edema is caused by congestive hydrostatic forces
Massive intrapulmonary ________ is a key pathophysiologic event in ARDS. Shunting
Shunting in ARDS is secondary to what 3 events? Wide-spread atelectasis Collapse of alveoli Surfactant dysfunction
How does shunting in ARDS manifest clinically? Severe hypoxia with no significant improvement on 100% oxygen
ARDS requires high _____ to prop airways open PEEP
Which patients have highest risk of developing ARDS? Sepsis or septic shock patients
In addition to massive shunting, what are 3 other pathophysiologic features of ARDS? - Decreased pulmonary compliance - Increased dead space - Low vital capacity & FRC
With ARDS, improvement on CXR lags behind clinical improvement by ________. 1 to 2 weeks +
Most useful parameter in differentiating ARDS from cariogenic pulmonary edema Post-capillary wedge pressure (PCWP) Low PCWP (<18) suggests ARDS Higher suggests cardiogenic edema
T/F: Routine placement of pulmonary artery catheters to determine PCWP has been shown to benefit ARDS patients. False
Treatment of ARDS - Oxygenation (to >90% sat) - Mechanical ventilation with high PEEP and low tidal volumes - Fluid management; maybe pressors - Treat underlying cause
7 possible complications of ARDS 1. Permanent lung injury 2. Mechanical ventilation-related problems: barotrauma, nosocomial PNA 3. Line-associated infections 4. Renal failure 5. Ileus, stress ulcers 6. Multi-organ failure 7. Critical illness myopathy

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