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PHARMACOLOGICAL ASPECTS OF HYPOTHALAMUS / PITUITARY & ADRENAL DISORDERS

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Mapa Mental sobre PHARMACOLOGICAL ASPECTS OF HYPOTHALAMUS / PITUITARY & ADRENAL DISORDERS, criado por Zulhilmi Zainal em 14-04-2014.
Zulhilmi Zainal
Mapa Mental por Zulhilmi Zainal, atualizado more than 1 year ago
Zulhilmi Zainal
Criado por Zulhilmi Zainal mais de 12 anos atrás
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Resumo de Recurso

PHARMACOLOGICAL ASPECTS OF HYPOTHALAMUS / PITUITARY & ADRENAL DISORDERS
  1. physiology
    1. Growth Hormone
      1. somatropin,somatrem(synthetic analog)
        1. To improve growth in children with GH deficiency
          1. Adverse
            1. Carpal tunnel syndrome, hyperglycemia
            2. Somatostatin
              1. Somatotropin releasing inhibiting hormone
                1. Synthetic
                  1. 1 Octreotide 2 Pegvisomant
                    1. uses
                      1. Acromegaly. Carcinoid tumors. Pancreatic tumors
                      2. Adverse
                        1. sludge(gallstone)
                  2. ERGOT DERIVATIVES (DOPAMINE AGONIST (D2)
                    1. Decrease prolactin
                      1. Bromocriptine
                        1. USES
                          1. Hyperprolactinemia
                            1. Parkinsonism
                            2. effecs
                              1. syncope,postural hypotension, psychosis
                            3. Vassopressin
                              1. ADH
                                1. Uses
                                  1. Neurogenic DI(pituitary)(central DI)
                                    1. Nephrogenic DI(impaired renal response to AVP)
                                      1. Constrict blood vessel
                                      2. Adverse
                                        1. coronary vasospasm
                                          1. uterine contraction
                                        2. Desmopressin
                                          1. selective (V2) agonist
                                            1. Uses
                                              1. DI(Central,pituitary)(DOC) Bedwetting(children)
                                            2. Adenocorticosteroids
                                              1. MAGIC drug
                                                1. Synthesis
                                                  1. uses
                                                    1. ALL Disease usable
                                                      1. Neurologic diseases
                                                        1. Pulmonary diseases
                                                          1. Renal disease
                                                      2. Immunosuppression
                                                        1. TOXICITY
                                                          1. Acute withdrawal
                                                            1. cerebral edema
                                                              1. fever, myalgia
                                                              2. Prolonged usage
                                                                1. fluid/lyte disturbances, hypertension, hyperglycemia, glycosuria
                                                                  1. peptic ulcers, osteoporosis (direct inhibition of osteoblasts) myopathy, cataracts

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