1. YES/NO: The following is concerning and requires further Ix/review:
A) 4 month old girl with a neutrophil count of 0.9 x 10^9/L

1. YES/NO: The following is concerning and requires further Ix/review:
B) 2 year old boy with recurrent otitis media and a neutrophil count varying between 0.2–1.0 x 10^9/L

1. YES/NO: The following is concerning and requires further Ix/review:
C) 10 year old girl from Sudan with a neutrophil count of 1.0 x 10^9/L

1. YES/NO: The following is concerning and requires further Ix/review:
D) 15 year old boy with neutrophil count of 0.6 x 10^9/L after rituximab for renal disease

2. 11 month old twins, previously well and thriving. 6 weeks of recurrent skin infections now growing pseudomonas. Apart from the skin lesions, exam normal. Both neutropenic (0.1 x 10^9/L). Bone marrow examination: normocellularity with increased myeloid activity with a left-shift and with reduction in mature forms; small amount of neutrophil phagocytosis; normal erythroid and megakaryocytic activity, no evidence of leukaemia. Most likely Dx:
A. Severe congenital neutropenia
B. Alloimmune neutropenia
C. Autoimmune neutropenia of infancy
D. Hypersplenism

3. Which of the following features is most consistent with a diagnosis of ITP
A) Absence of dysmorphic features
B) Elevated MCV for age
C) History of easy bruising since infancy
D) Reduced Hb for age
E) Presence of hepatosplenomegaly