Protein Structure Pt. 1

One that contains only amino acid residues

One that contains prosthetic groups

One that is bound to a membrane

Heteromultimer

Homomonomer

Homomultimer

Fibrous

Globular

Membrane spanning

They are hydrophobic

They are hydrophillic

Independent folding units of the tertiary structure that have independent functions

Independent folding units of tertiary structure that have related functions

Dependent folding units of secondary structure that have relation functions

Dependent folding units of tertiary structure that have related functions

Independent structures in a quaternary structure

Independent structures in a tertiary structure

Dependent subunits in a quaternary structure

Osteoarthritis

Osteogenesis imperfecta

Osteocalcification

Where bond pairs cannot be described as a single Lewis Diagram

Where two atoms in separate molecules cause each other to vibrate

Where two atoms in separate molecules are more likely to bond to each other than to another atom

Between the carbonyl carbon and the alpha carbon

Between the alpha carbon and the amide group

Between the alpha carbon and the R group

Between the alpha carbon and the amide group

Between the alpha carbon and the carbonyl carbon

Between the alpha carbon and the R group

Where the charge of an atom prevents it from being close to another

Where the electron arrangement of an atom prevents it from being close to another

Where the size of an atom prevents it from being close to another

It has a double bond like structure

It's electrons clash with that of the psi bond

It's electrons clash with the phi bond

3.4

3.5

3.6

1.5 angstroms

1.6 angstroms

1.7 angstroms

Carbonyl oxygen 4 amino acids away

Carbonyl oxygen 6 amino acids away

Carbonyl oxygen 8 amino acids away

12

13

14

To allow beta sheets to reverse direction

To connect beta sheets together

To link protein subunits together

It decreases entropy

They're hydrophobic in a hydrophillic environment

They prevent the protein from folding correctly

lowest energy

Highest energy

Easiest energy to reach (energy closest to that of unfolded protein)

A local low energy minimum

A local high energy minimum

Reversible secondary structure formation

Reversible tertiary structure formation

Reversible quaternary structure formation