Jeku Jacob
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RACP Endocrinology (Management of Diabetes) Quiz sobre Management of diabetes , criado por Jeku Jacob em 26-04-2016.

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Jeku Jacob
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Management of diabetes

Questão 1 de 6

1

Which of the following mechanisms best describes the mode of action of the sulphonylurea class of drugs?

Selecione uma das seguintes:

  • Stimulates insulin synthesis.

  • Enhances insulin binding to the beta cell insulin receptor.

  • Stimulates insulin secretion.

  • Stimulates conversion of proinsulin to insulin and C-peptide.

  • Stimulates beta cell proliferation.

Explicação

Questão 2 de 6

1

The deterioration in glycaemic control over time seen in patients with type 2 (non-insulin-dependent) diabetes mellitus is primarily due to:

Selecione uma das seguintes:

  • medication non-compliance.

  • increasing insulin resistance.

  • increasing obesity.

  • decreasing insulin secretion.

  • reduced energy expenditure

Explicação

Questão 3 de 6

1

Which of the following drugs used in diabetes treatment is most likely to cause hypoglycemia?

Selecione uma das seguintes:

  • Repaglinide.

  • Metformin.

  • Acarbose.

  • Rosiglitazone.

  • Orlistat.

Explicação

Questão 4 de 6

1

In a patient with Type 2 diabetes which of the following co-existing clinical situations is the strongest contraindication to the use of a thiazolidinedione drug?

Selecione uma das seguintes:

  • Fatty liver disease.

  • Peripheral vascular disease.

  • Severe congestive cardiac failure.

  • Proliferative diabetic retinopathy.

  • Serum creatinine 200μmol/L.

Explicação

Questão 5 de 6

1

In patients with Type 1 Diabetes, the greatest benefit in using a long acting insulin analogue is in reducing which of the following

Selecione uma das seguintes:

  • Diabetic Retinopathy

  • Nocturnal hypoglycemia

  • insulin hypersensitivity

  • preprandial hyperglycemia

  • microalbuminuria

Explicação

Questão 6 de 6

1

Glucagon-like peptide–1, secreted postprandially by the L-cells in the intestine, increases which of the following?

Selecione uma das seguintes:

  • Gastric emptying.

  • Body weight.

  • Insulin secretion.

  • Hepatic glucose output.

  • Insulin sensitivity (sulphonylurea, thiazolidinediones)

Explicação

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