current molecular therapies undergoing trials for cancer treatment

Sleeping beauty transposons; a non-viral vector for gene therapy

major problem with adenoviruses as vectors

advantages of retroviruses as viral vectors

disadvantages of retroviruses as vectors

advantages and disadvantages of adenoassociated viruses as vectors

somatic germline therapy

germline therapy

2 types of gene therapy

liposomes as vector

antibodies as vectors

particle bombardment as vector

ligands as vectors

take home message re gene augmentation therapy

tissues targeted for gene augmentation therapy

major problems with gene augmentation therapy

criteria for gene therapy

what type of viral vectors available for gene therapy?

non viral vectors for gene therapy

problems with human organs for donations

problems with animal organs for human use

what are the general problems with organs for donation

what types of recombinant protiens may be used in theraputic strategies?

adenoviruses as vectors

how to engineer transgenic pig for xenotransplantation

5 molecular therapies for the treatment of cancer

an example of recombinant protien therapy for cancer treatment

an example of organ transplant for cancer treatment

an example of how stem cells are used for cancer treatment

describe reproductive stem cell therapy

describe theraputic stem cell therapy

list 6 potential problems associated with production of a theraputic monoclonal antibody

name 6 vector properties important in human gene therapy

what is a SNP?

(single nucleotide polymorphism)

Where do most SNPS occur?

what happens when a SNP occurs within the coding sequence?

how often to SNPs occur?

how many common SNPs are there?

what responses do SNPs affect? (5)

how are SNPs useful in drug therapy?

how would poor and rapid metabolisers respond to a prodrug like codiene?

how would poor/rapid metabolisers respond to an active drug like omeprazole?

what would be the impact of global testing for SNPs?

antidepressants and SNPs

problems associate with production of recombinant protiens (9)

what are 2 vector types for human gene therapy?