Vincent Conquer
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The Anatomy and Function of a Myofibril

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Vincent Conquer
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The Anatomy and Function of a Myofibril, Myofilaments, Actin, Myosin other proteins

Questão 1 de 12

1

What is a myofibril?

Selecione uma das seguintes:

  • the muscle fiber

  • the actin filament

  • the myosin filament

  • columnar protein columns alongside the muscle fiber

Explicação

Questão 2 de 12

1

Bodily movements or motion occur when muscles contract or shorten. Which of the following best describes how this occurs?

Selecione uma das seguintes:

  • kk

  • Actin, when polymerized into filaments, forms the "ladder" along which the myosin filaments "climb" to generate motion.

Explicação

Questão 3 de 12

1

Six different proteins and molecules participate in the contraction of a sarcomere, namely:
myosin
actin
tropomyosin
troponin
ATP
Ca2+ ions
 
Some of these combine together to form thick and thin filaments.

Read more: http://slidingfilament.webnode.com/sliding-filament-theory/

Selecione uma das seguintes:

  • kk

  • jj

Explicação

Questão 4 de 12

1

a) Thick filaments - The thick filament is composed of myosin. The projections from the myosin filament are called crossbridges. The crossbridge is believed to be a molecular motor that converts chemical energy into mechanical work.

b) Thin filaments - The thin filament is composed of actin, troponin, and tropomyosin.

Selecione uma das seguintes:

  • k

  • o

Explicação

Questão 5 de 12

1

Regulatory proteins are :

Selecione uma das seguintes:

  • myosin is a contractile filament

    titin and nebulin are structural proteins

    contractile protein , Actin
    -consists of 2 alpha helical strands of g-actin molecules bonded in series
    -each g-actin has a binding site where the s1 fragment of the myosin cross-bridge complex binds during muscle contraction

    -contractile protein, myosin
    -consists of two heavy (form tail region and two cross-bridges that bind with actin to produce force) and four light chains (that influence cross-bridge cycling kinetics and therefore sarcomere contraction velocity

    -contractile protein
    -consists of two heavy (form tail region and two cross-bridges that bind with actin to produce force) and four light chains (that influence cross-bridge cycling kinetics and therefore sarcomere contraction velocity

    Muscle contractile protein
    Heart and muscle contractile fibres consist of bundles of actin polymers that slide alongside each other by the activity of the motor protein myosin and associated contractile proteins such as troponin and titin

    Muscle contractile protein
    Heart and muscle contractile fibres consist of bundles of actin polymers that slide alongside each other by the activity of the motor protein myosin and associated contractile proteins such as troponin and titin

    regulatory proteins
    proteins that help turn the muscle contraction process on and off

    contractile proteins
    proteins that produce force during muscle contraction

    structural proteins
    proteins that connect the outer layer of myofibrils to the sarcolemma, keep the actin and myosin filaments in proper alignment, and give the myofibrils their elasticity and extensibility

    tropomyosin
    -two per actin filament
    -when muscle is relaxed, covers the myosin-head binding sites on the actin filament

    troponin
    -binds to both actin and tropomyosin
    -has binding site for Ca+2 needed for muscle contraction
    -located at the junction of each successive pair of tropomyosin molecules

    titin
    -stabilizes the alignment of the thick filaments by connecting each myosin filament to both the z line and the m line
    -the titin that extends from the z line to the beginning of the myosin filament is believed to help keep the myosin filaments centered between the z lines
    -helps the sarcomere return to its resting length after the muscle has contracted or been stretched, contributing to the myofibril's elasticity and extensibility

    nebulin
    -extends the length of each actin filament
    -believed to anchor the actin filament to the z-line and help regulate the length of the actin filament

    actin
    -contractile protein
    -consists of 2 alpha helical strands of g-actin molecules bonded in series
    -each g-actin has a binding site where the s1 fragment of the myosin cross-bridge complex binds during muscle contraction

    myosin
    -contractile protein
    -consists of two heavy (form tail region and two cross-bridges that bind with actin to produce force) and four light chains (that influence cross-bridge cycling kinetics and therefore sarcomere contraction velocity

  • proteins that help turn the muscle contraction process on and off

  • proteins that regulate bodily systems and are used in homeostasis

Explicação

Questão 6 de 12

1

Titin and nebulin are structural proteins

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 7 de 12

1

actin
- is a contractile protein
-consists of 2 alpha helical strands of g-actin molecules bonded in series
-each g-actin has a binding site where the s1 fragment of the myosin cross-bridge complex binds during muscle contraction

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 8 de 12

1

myosin

Selecione uma das seguintes:

  • -is a contractile protein

  • -consists of two heavy (form tail region and two cross-bridges that bind with actin to produce force) and four light chains (that influence cross-bridge cycling kinetics and therefore sarcomere contraction velocity

  • is a myofilament , a filament of a myofibril

  • All of these are true

Explicação

Questão 9 de 12

1

contractile proteins

Selecione uma das seguintes:

  • proteins that produce force during muscle contraction

  • proteins that bind with troponin

  • are centered with the M-line

  • proteins that build muscle

Explicação

Questão 10 de 12

1

structural proteins:
proteins that connect the outer layer of myofibrils to the sarcolemma, keep the actin and myosin filaments in proper alignment, and give the myofibrils their elasticity and extensibility

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 11 de 12

1

tropomyosin:

Selecione uma das seguintes:

  • There are two per actin filament.
    Tropomyosin, when muscle is relaxed, covers the myosin-head binding sites on the actin filament.

  • is a myofilament

  • has a calcium ion attached to it

  • is located in the neuromuscular junction

Explicação

Questão 12 de 12

1

Preencha os espaços em branco para completar o texto.

Titin
-stabilizes the alignment of the thick filaments by connecting each myosin filament to both the
-the titin that extends from the z line to the beginning of the myosin filament is believed to
-helps the after the muscle has contracted or been stretched, contributing to the

nebulin
-extends the length of each actin filament
-believed to anchor the actin filament to the z-line and help regulate the length of the actin filament

actin
-contractile protein
-consists of 2 alpha helical strands of g-actin molecules bonded in series
-each g-actin has a binding site where the s1 fragment of the myosin cross-bridge complex binds during muscle contraction

myosin
-contractile protein
-consists of two heavy (form tail region and two cross-bridges that bind with actin to produce force) and four light chains (that influence cross-bridge cycling kinetics and therefore sarcomere contraction velocity

Explicação