Question 1
Question
A 63 year old woman develops breast cancer. Which of the following is the most likely manner in which the cancer will become noticeable
Answer
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she is anemic
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she develops an opportunistic infection
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she develops a cough with bloody sputum production
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she has pain with breathing
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she feels a lump during her monthly breast self-examination
Question 2
Question
Which of the following has NOT been implicated in causing cancer
Answer
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exposure to high-voltage power lines
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viral carcinogens, such as HPV
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exposure to ultraviolet radiation (sunlight)
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chemicals in foods, such as aflatoxin
Question 3
Question
Which of the following is not an example of physiologic hyperplasia?
Answer
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Breast development in adolescent females
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Breast enlargement in males
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A well-conditioned athlete’s enlarged heart
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Uterine size increase during pregnancy
Question 4
Question
The first step a cell must undergo to acquire autonomous growth potential is called:
Answer
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Progression
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Transformation
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Alteration
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Initiation
Question 5
Question
Specialized copies of DNA that code for growth factors contributory to neoplasia are called:
Answer
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Mutations
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Promoters
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Tumor suppressor genes
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Oncogenes
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Initiators
Question 6
Question
Chemotherapy is generally most effective with tumors composed fo rapidly dividing cells.
Question 7
Question
The most aggressive growths will appear this way under microscopic examination
Answer
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poorly differentiated
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well differentiated
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low grade
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atypical
Question 8
Question
Examples of chemical carcinogens include all of the following except:
Answer
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cigarette smoke
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vinyl chloride
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ultraviolet radiation
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human papillomavirus
Question 9
Question
The most common cancer in women is _a. __________ cancer, but more women die of _b._______________ cancer.
Answer
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a. lung b. breast
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a. breast b. lungs
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a. cervix b. breast
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a. lungs. b. cervix
Question 10
Question
An agent that causes cancer is
Answer
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carcinogen
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initiator
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transformer
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oncogene
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promoter
Question 11
Question
A 53 year old woman undergoes a breast biopsy. The pathology report states that some of the breast ducts demonstrate epithelial hyperplasia. Based on your understanding of hyperplasia, what do you think is the most appropriate advice to give this woman?
Answer
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She should have mammograms at more frequent intervals.
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She should return in 1-2 years for her regular screening mammogram
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She should undergo brain imaging because she might have a pituitary adenoma.
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She should have a pregnancy test.
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She should have a mastectomy to remove all premalignant tissue.
Question 12
Question
A neoplasm that will likely not kill the individual that harbors it
Answer
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Benign
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malignant
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invasion
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in situ
Question 13
Question
A neoplasm that has the potential to spread widely and cause death
Answer
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malignant
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in situ
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benign
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invasion
Question 14
Question
The direct extension of neoplastic cells into surrounding tissue without regard to tissue boundaries
Answer
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benign
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malignant
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in situ
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invasion
Question 15
Question
Metaplasia is the replacement of one tissue type by another
Question 16
Question
Which of the following contribute to accurate staging of a cancer
Answer
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A. Knowing the size of the tumor and the extent to which it has invaded local tissues
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B. Knowing whether there are metastases to regional lymph nodes
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Knowing whether there are metastases to distant organs.
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Knowing the size of distant organ metastases.
Question 17
Question
Which of the following names suggests a benign neoplasm when, in fact, it is malignant?
Answer
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lymphoma
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chondroma
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fibrosarcoma
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papilloma
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lipoma
Question 18
Question
In the context of neoplasia, “stage” refers to:
Answer
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The size of the tumor.
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The amount of functional disability the tumor has caused.
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The degree of atypia of malignant cells.
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The extent of spread of a cancer through the body.
Question 19
Question
Carcinoma is a malignant neoplasm of mesenchymal tissues
Question 20
Question
Hormonal therapy plays a significant role in the regression of breast and prostate cancer.