Pharmacology- Fluoroquinolones- 4th Year PMU

Description

Pharmacology- Fluoroquinolones- 4th Year PMU
Med Student
Quiz by Med Student , updated more than 1 year ago
Med Student
Created by Med Student over 5 years ago
101
3

Resource summary

Question 1

Question
Fluoroquinoiones are:
Answer
  • Gentamycin
  • Moxifloxacin
  • Ciprofloxacin
  • Levofloxacin

Question 2

Question
Mechanism of action of quinolones is:
Answer
  • inhibition of protein synthesis
  • inhibition of cell wall synthesis
  • inhibition of topoisomerase II and IV
  • inhibition of DNA transcription and replication

Question 3

Question
Fluoroquinolones have:
Answer
  • broad antibacterial spectrum
  • narrow antibacterial spectrum
  • bacteriostatic effect
  • bactericidal effect

Question 4

Question
Point out the correct statements for pharmacokinetics of fluoroquinolones:
Answer
  • bad oral absorption and are administered always parenterally
  • distribute well into all tissues and body fluids
  • inhibit some liver cytochromes
  • most of them are excreted renally

Question 5

Question
Fluoroquinolones are used for treatment of:
Answer
  • Urinary tract infections
  • Respiratory infections
  • Skin infections
  • Gl infections

Question 6

Question
Adverse drug reactions of fluoroquinolones are:
Answer
  • articular cartilage erosion (arthropathy)
  • hypertension
  • seizures in patients with epilepsy
  • prolongation of QT interval

Question 7

Question
Quinolones are contraindicated in
Answer
  • pregnancy and breast-feeding
  • children under 18 years of age
  • patients with epilepsy
  • patients with renal failure

Question 8

Question
Drug interactions of fluoroquinolones are:
Answer
  • increase serum levels of theophyiline by inhibiting its metabolism
  • decrease serum levels of theophyiline by inducing its metabolism
  • synergism with beta-lactams
  • calcium and other divalent cations decrease their absorption
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