469527
Description
Quiz by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312
over 10 years ago
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Question 1
Question
In normal RBC destruction, globin is recycled and Fe is broken down
Answer
- True
- False
Question 2
Question
In Intravascular Haemolytic Anaemia, cells are lysed in the blood vessels
Answer
- True
- False
Question 3
Question
Why is Intravascular H.A so dangerous?
Answer
-
Hb dimers form in the blood and block the kidneys
-
R.B.C fragments block capillaries
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R.B.C's aggregate and block capillaries
Question 4
Question
Renal failure and Heamoglobinurea are caused by...
Answer
-
Intravascular
-
Extravascular
Question 5
Question
What is implicated in Extravascular Haemolytic Anaemia
Answer
-
The spleen
-
The bone marrow
-
The liver
Question 6
Question
In Extravascular, macrophage Fc receptors bind to the RBC's Ig's
Answer
- True
- False
Question 7
Question
Once bound, what happens to RBC's in Haemolytic Anaemia
Answer
-
A small portion of RBC membrane in ingested
-
RBC's a phagocytosed
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Leukocytes bind to RBC's
Question 8
Question
If small portions of RBC membrane is removed, what happens?
Answer
-
Cell becomes spherical and less malleable
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And is deformed by spleenic machinary
Question 9
Question
Loss of RBC's leads to low glucose in the spleen, which leads to...
Answer
-
Inc haemolysis
-
Fatigue
-
Inc risk of diabetes
Question 10
Question
Reticuloctosis- inc presence of reticulocytes
Answer
- True
- False
Question 11
Question
What causes reticulocytosis?
Answer
-
The body trying to replace lost R.B.C's but can't keep up production
-
The damaged R.B.Cs degenerate into reticulocytes
-
The lymphocytes attack R.B.Cs, making them degenerate into reticulocytes
Question 12
Question
In Drug Induced Haemolytic Anaemia, what happens?
Answer
-
Drug induced antibodies cross react
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Drug specific antibodies cross react
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Drugs cause R.B.C's to aggregate
Question 13
Question
Haemolytic Anaemias can be caused by physical stress....
Answer
-
Caused by heart valve turbulence
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Damage from fibrin strands
Question 14
Question
March Haemoglobinurea is damge to RBC's in small foot bones due to prolonged marching/running
Answer
- True
- False
Question 15
Question
Infections can cause H.A by altering R.B.C morphology
Answer
- True
- False
Question 16
Question
What's the difference between Immune and Autoimmune Haemolytic Anaemia?
Answer
-
Immune - Antibodies react with own RBC's Autoimmune - Antibodies react with transfused RBC's
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Autoimmune - Antibodies react with own RBC's Immune- Antibodies react with transfused RBC's
Question 17
Question
In some cases, an RBC transfusion can lead to degredation of the original RBC's
Answer
- True
- False
Question 18
Question
Name two types of Inherited Haemolytic Anaemia
Answer
-
Sickel Cell Anaemia
-
Thalassaemia
Question 19
Question
Hereditary Spherocytosis is caused by an abnormal membrane causing Spherical R.B.C's
Answer
- True
- False
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