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Virology (week 3 and 4)

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DVM2 Virology Quiz on Virology (week 3 and 4), created by Kathryn Borg on 26/04/2016.
Kathryn Borg
Quiz by Kathryn Borg, updated more than 1 year ago
Kathryn Borg
Created by Kathryn Borg almost 8 years ago
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Resource summary

Question 1

Question
Correctly describe the family of Poxviridae
Answer
  • Large complex structured viruses with a single molecule of ds DNA
  • Large complex structured viruses with a two molecules of ds RNA
  • Large complex structured viruses with a single molecule of ss DNA
  • Small complex structured viruses with a single molecule of ss DNA

Question 2

Question
What are the two sub-families within Poxviridae?
Answer
  • Chordopoxvirinae
  • Entomopoxvirinae
  • Alphaherpesvirinae
  • Papillomavirus
  • Orbivirus

Question 3

Question
What is this lesion?
Image:
2484d28c-43fb-49c3-837a-adbc8c789f50.gif (image/gif)
Answer
  • Pock
  • Pustule
  • Ulceration
  • Macule

Question 4

Question
What is the correct pathogenesis of a pock lesion?
Answer
  • Raised, reddened macule-->papule--> fluid filled vesicle-->Ruptures to form a crater (pock)-->Scarring
  • papule--> Raised, reddened macule--> fluid filled vesicle-->Ruptures to form a crater (pock)-->Scarring
  • fluid filled vesicle-->papule--> Raised, reddened macule-->Ruptures to form a crater (pock)-->Scarring

Question 5

Question
What is true of pox viruses?
Image:
999a66cc-96b2-4964-a67d-ea87d43dd9ab.gif (image/gif)
Answer
  • Duration of immunity < life span of recovered animal
  • Reinfection possible
  • Surviving animals are NOT long term carriers
  • Infectious virus survives for years in infected material (scabs)
  • Pox viruses are very resistant in the environment
  • Surviving animals ARE long term carriers
  • Pox viruses are labile in the environment
  • Immunity is for life

Question 6

Question
Poxvirus transmission between animals may occur by?
Image:
92b74baa-3b9c-4059-9f1b-de2c8219331b.gif (image/gif)
Answer
  • Mechanical transmission
  • Respiratory route by droplets
  • Via abraded skin

Question 7

Question
Label this diagram correctly. Matching the correct genus with the virus groups (a-f)
Image:
e6df1070-b5e9-4b00-9518-8f53578672a4.gif (image/gif)
Answer
  • Orthopoxvirus
  • Parapoxvirus
  • Capripoxvirus
  • Avipoxvirus
  • Suipoxvirus
  • Leporipoxvirus

Question 8

Question
What is true of cowpox?
Image:
0ae09059-d2f9-4a97-b19a-77191a327c37.gif (image/gif)
Answer
  • Rodent reservoir
  • Endemic in Europe and Russia and exotic to Australia
  • Results in pock lesions on teats
  • Can affect humans causing maculopapular lesions on hands and face
  • Can affect domestic and large cats
  • Endemic to Australia
  • Mosquito reservoir

Question 9

Question
Sheeppox, Lumpy skin disease and Goat pox are closely related viruses that are indistinguishable by serological assays
Answer
  • True
  • False

Question 10

Question
How might an animal become infected by a Capripoxvirus (sheeppox, lumpy skin disease and goat pox)?
Answer
  • Skin abrasions
  • Inhalation of aerosols
  • Vector transmission
  • Gastrointestinal tract infection

Question 11

Question
Where are the Capripoxviruses (sheeppox, lumpy skin disease and goat pox) endemic to?
Answer
  • Endemic in SE Europe, Middle East, Africa and Asia
  • Endemic in North America, Northern Europe and Australia
  • Endemic in North America and Australia
  • Endemic in North America, the UK, Africa and Asia

Question 12

Question
What is the pathogenesis of the Capripoxviruses (sheeppox, lumpy skin disease and goat pox)?
Answer
  • Replicates locally in skin
  • Replicates in lungs following inhalation
  • Can spread to regional lymph nodes
  • Replicates in the gut when swallowed
  • Replicates in lymphocytes

Question 13

Question
What is the incubation period of the Capripoxviruses (sheeppox, lumpy skin disease and goat pox)?
Answer
  • ~ 1 week
  • ~ 3 weeks
  • ~ 2 weeks
  • ~ 1 day

Question 14

Question
How might fowl pox be transmitted between animals?
Image:
8600bdc3-53f3-437e-a960-4e45b3f49fd4.gif (image/gif)
Answer
  • Mechanical transmission via mosquitos
  • Aerosol transmission
  • GIT transmission

Question 15

Question
Fowl pox is found within what genus of poxviridae?
Answer
  • Avipoxvirus
  • Capripoxvirus
  • Orthopoxvirus
  • Parapoxvirus

Question 16

Question
What is the Parapoxviruses Orf also called?
Answer
  • Scabby Mouth
  • Contagious pustular dermatitis
  • Contagious ecthyma

Question 17

Question
What is this disease most likely to be if it is from the poxviridae family?
Image:
8f9ef794-6f29-44f2-a270-42ee6c922c87.gif (image/gif)
Answer
  • Orf
  • Bovine Papilloma virus
  • Foot and mouth disease

Question 18

Question
What is true of the pathogenesis and epidemiology of Orf?
Answer
  • Papular lesions progress to vesicles, pustules and then scabs
  • Lesions heal within 4 weeks (if no secondary bacterial infection)
  • Replicates in epidermal keratinocytes
  • Controlled by virulent vaccination
  • Lesions usually on lips and muzzle (feet, genitalia and teats)
  • Maintained in flocks by chronic carriers
  • Transmission via abrasions
  • Primarily a disease of young sheep
  • There are NO carrier animals
  • There is no vaccination available

Question 19

Question
What is Myxomatosis?
Answer
  • A poxvirus disease of rabbits
  • A papillomavirus disease of dogs
  • A poxvirus disease of dogs
  • A poxvirus disease of cats

Question 20

Question
Correctly describe the family of Asfarviridae?
Answer
  • They are complex enveloped double stranded DNA virus
  • They are complex enveloped single stranded DNA virus
  • They are complex non-enveloped double stranded DNA virus
  • They are complex enveloped double stranded RNA virus
  • They are complex non-double stranded RNA virus

Question 21

Question
Asfarviridae is Stable in the environment over a wide range of temperatures (4‐20oC) and a wide range of pH. It may persist for months in meat of infected pigs.
Answer
  • True
  • False

Question 22

Question
Which of the below viruses belong to the family Asfarviridae?
Answer
  • African Swine Fever Virus
  • African Horse Sickness
  • Foot and Mouth Disease (FMD)
  • Contagious pustular dermatitis

Question 23

Question
What animals can Asfarviridae infect?
Answer
  • Soft ticks (Ornithodorus moubata and O erraticus)
  • Suidae (eg. pigs, warthogs)
  • Felidae (Domestic cats, lions, tigers)
  • Bovidae (cattle, ox)
  • Canidae (dogs, wolves)
  • Blow flies (Lucillia cuprina, Calliphora stygia)

Question 24

Question
Is a vaccine available for African Swine Fever Virus?
Answer
  • Yes
  • No

Question 25

Question
Where does the virus grow within the body?
Answer
  • In the reticuloendothelial system
  • In the respiratory sytem
  • In the nervous system
  • In the gastrointestinal system

Question 26

Question
Are there carriers of African swine fever virus?
Answer
  • Yes
  • No

Question 27

Question
Why might an animal with African Swine Fever Virus die?
Image:
9270fc8e-07eb-4ac9-beaa-a808e21fc162.gif (image/gif)
Answer
  • Extensive haemorrhages in all organs due to platelet damage and complement activation
  • Damage to the CNS causing the lungs to collapse
  • Oedamatous fluid in the lungs

Question 28

Question
Describe the Herpesviruses?
Answer
  • Enveloped double stranded DNA viruses
  • Non-Enveloped double stranded DNA viruses
  • Enveloped single stranded DNA viruses
  • Non-enveloped single stranded DNA viruses

Question 29

Question
Why are the herpesviruses labile in environment and easily inactivated by heat, detergents, pH and drying?
Answer
  • They are enveloped viruses
  • They are non-enveloped viruses
  • They are capsulated viruses

Question 30

Question
How are Herpesviruses transmitted?
Answer
  • Close or mucosal contact for transmission (droplet)
  • GIT transmission
  • Vector transmission

Question 31

Question
What is the key feature of Herpesviruses?
Answer
  • They cause a lifelong latent infection
  • They cause 100% mortality in the infected
  • Infection results in lifelong immunity

Question 32

Question
What are the sub families of Herpesviridae?
Answer
  • Alphaherpesvirinae
  • Gammaherpesvirinae
  • Betaherpesvirinae
  • Deltaherpesvirinae
  • Alloherpesvirinae

Question 33

Question
Match the correct virus sub families to their features
Image:
a3f82101-a23c-4b47-84f7-1ffc4a43e15a.gif (image/gif)
Answer
  • Gammaherpesvirinae
  • Betaherpesvirinae
  • Alphaherpesvirinae
  • Deltaherpesvirinae

Question 34

Question
Bovine herpesvirus 1 (Infectious bovine rhinotracheitis virus) can manifest as which of the below clinical diseases?
Answer
  • Rhinotracheitis
  • Generalised disease of newborn calves
  • Enteritis
  • Abortion
  • Conjunctivitis
  • Balanoposthitis
  • Vulvovaginitis

Question 35

Question
How is Bovine Herpesvirus 1 transmitted?
Answer
  • Respiratory route and cell associated viraemia to distant sites
  • GIT route
  • Fomites
  • Vector transmission

Question 36

Question
Bovine herpesvirus 2 -- Bovine mammillitis virus (Pseudo‐lumpy skin disease virus) can cause which of the below forms of clinical disease
Answer
  • Mammillitis. Lesions localised to the teats.
  • Generalised skin lesions. Nodules & necrosis of the superficial epidermis
  • Abortion
  • Rhinotracheitis

Question 37

Question
Bovine herpes virus 5 causes?
Answer
  • Fatal meningoencephalitis in calves thought to be due to direct neural spread from nasopharynx via trigeminal nerve
  • Respiratory disease, abortion and neurological disease in foals
  • Acute respiratory disease characterised by nasal discharge and lymphadenopathy in calves
  • A variety of clinical diseases

Question 38

Question
What is the most important viral cause of abortion in horses worldwide?
Answer
  • Equine herpesvirus 1
  • Equine herpesvirus 4
  • Bovine herpes virus 1
  • Equine sarcoid virus
  • African horse sickness

Question 39

Question
When do abortions usually occur in EHV 1?
Answer
  • Usually late gestation
  • Usually early gestation
  • Usually mid gestation
  • Abortions do not usually occur

Question 40

Question
How can you prevent EHV1 from spreading
Answer
  • Small groups based on foaling date
  • Pregnant mares be kept separate from other horses
  • There is a vaccine available
  • Cull all animals with the virus

Question 41

Question
How long is the aborting mare infectious for?
Answer
  • 1‐2 days from reproductive tract and up to 2 weeks from the respiratory tract
  • 5-10 days from reproductive tract and up to 6 weeks from the respiratory tract
  • 5‐6 days from reproductive tract and up to 4 weeks from the respiratory tract

Question 42

Question
How can EHV1 and EHV4 be differentiated?
Answer
  • ELISA test for antibody
  • Electron microscopy
  • Viral culture

Question 43

Question
Which age group of horses show the most severe clinical signs to EHV4
Answer
  • Weanling and yearlings (juveniles)
  • Adults
  • Old horses

Question 44

Question
Feline herpesvirus 1 (Feline rhinotracheitis) causes?
Answer
  • acute respiratory disease characterised by nasal discharge, ocular discharge, sneezing, dyspnoea and occasional oral ulcers
  • fatal meningoencephalitis in kittens thought to be due to direct neural spread from nasopharynx via trigeminal nerve
  • abortion of kittens during late gestation
  • generalised skin lesions. Nodules & necrosis of the superficial epidermis

Question 45

Question
Gallid herpesvirus 1 is also known as?
Answer
  • Infectious laryngotracheitis
  • Gallid rhinopneumonitis
  • Gallid encephalitis virus
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