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Immunology 2

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Quiz by 0 9, updated more than 1 year ago
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Created by 0 9 over 7 years ago
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Resource summary

Question 1

Question
Which options are primary lymphoid organs?
Answer
  • Thymus
  • Bone marrow
  • Spleen
  • Peyer's patches
  • MALT

Question 2

Question
Which options are secondary lymphoid organs?
Answer
  • MALT
  • Spleen
  • Lymph nodes
  • Thymus
  • Bone marrow

Question 3

Question
Dendritic cells are derived from lymphoid and myeloid precursors.
Answer
  • True
  • False

Question 4

Question
Platelets are derived directly from pluripotent stem cells.
Answer
  • True
  • False

Question 5

Question
Which options do not express MHC Class 1?
Answer
  • Red blood cells
  • Platelets
  • Neutrophils
  • B cells
  • T cells

Question 6

Question
Naive B cells are derived from the
Answer
  • Bone marrow
  • Thymus
  • Spleen
  • MALT

Question 7

Question
CD4+ T cells recognise
Answer
  • MHC Class 1
  • MHC Class 2

Question 8

Question
CD8+ T cells recognise
Answer
  • MHC Class 1
  • MHC Class 2

Question 9

Question
CD16 and CD56 are both found on
Answer
  • NK cells
  • Macrophages
  • B cells
  • T cells

Question 10

Question
All leukocytes express
Answer
  • CD45
  • CD19
  • CD68
  • CD59

Question 11

Question
The most abundant leukocyte in circulation are...
Answer
  • Neutrophils
  • Macrophages
  • B cells
  • CD8+ T cells

Question 12

Question
Monocytes and Macrophages help to produce components involved in the complement system
Answer
  • True
  • False

Question 13

Question
Macrophages are able to present antigens on their surface
Answer
  • True
  • False

Question 14

Question
Monocytes have CD.....
Answer
  • 14
  • 56
  • 16
  • 15

Question 15

Question
During phagocytosis, fusion of the lysosome and phagosome leads to production of...
Answer
  • Phagolysosome
  • Early endosome
  • Endophagosome

Question 16

Question
Which granulocytes have major basic protein in their granules?
Answer
  • Eosinophils
  • Basophils
  • Neutrophils

Question 17

Question
Which granulocytes have lactoferrin in their granules?
Answer
  • Neutrophils
  • Eosinophils
  • Basophils

Question 18

Question
Which granulocytes do not have histamine in their granules?
Answer
  • Eosinophils
  • Neutrophils
  • Basophils

Question 19

Question
Which granulocytes have chondroitin sulphate in their granules?
Answer
  • Neutrophils
  • Eosinophils
  • Basophils

Question 20

Question
Which of these are reactive oxygen species?
Answer
  • Hypochlorous acid
  • Hydrogen peroxide
  • Superoxide
  • Water

Question 21

Question
The only antimicrobial peptides that macrophages use are...
Answer
  • Cathelicidins
  • Azurocidin
  • Defensins
  • Histatins

Question 22

Question
Acidification by neutrophils or macrophages is...
Answer
  • Bacteriocidal
  • Bacteriostatic
  • Can be both

Question 23

Question
Both macrophages and neutrophils produce ROS's.
Answer
  • True
  • False

Question 24

Question
Both macrophages and neutrophils produce NETs.
Answer
  • True
  • False

Question 25

Question
The most potent antigen present cell is...
Answer
  • Dendritic cells
  • Macrophages
  • Monocytes
  • B cells

Question 26

Question
Label the features of platelets
Image:
525ac385-b8ba-4817-a1b0-ca9ffc202be9 (image/png)
Answer
  • platelet
  • ctivating
  • fibrinogen
  • ytokines
  • C3b

Question 27

Question
Most T cells are...
Answer
  • CD4 positive but CD8 negative
  • CD4 positive and CD8 positive
  • CD8 positive but CD4 negative

Question 28

Question
Which cytokine results in a T cell receptor being produced on an immature T cell?
Answer
  • IL-7
  • IL-10
  • GM-CSF
  • TNF-a

Question 29

Question
Self molecules are said to induce...
Answer
  • Tolerance
  • Multi-specificity
  • Immunogenicity

Question 30

Question
What is negative selection?
Answer
  • T cells with a high affinity for self antigens are killed by apoptosis
  • T cells with a high avidity for self antigens are killed by apoptosis
  • T cells with a low affinity for self antigens are killed by apoptosis
  • T cells with a low affinity for self antigens are allowed to mature

Question 31

Question
What is positive selection?
Answer
  • T cells with a low affinity for self antigens are allowed to mature
  • T cells with a high affinity for self antigens are allowed to mature
  • T cells with a high affinity for self antigens are killed off by apoptosis
  • T cells with a low affinity for self antigens are killed off by apoptosis

Question 32

Question
The majority of T cells do not make it through negative selection.
Answer
  • True
  • False

Question 33

Question
T cells without any stimulation also die off.
Answer
  • True
  • False

Question 34

Question
What CD do T regulatory cells have?
Answer
  • 4
  • 19
  • 8

Question 35

Question
Which cells do TH1 helper cells activate?
Answer
  • Macrophages
  • B cells
  • Any nucleated cell
  • Stromal cells

Question 36

Question
Which cells do TH2 helper cells activate?
Answer
  • B cells
  • Macrophages
  • T cells
  • Stromal cells

Question 37

Question
Which cells do TH17 helper cells activate?
Answer
  • Stromal cells
  • B cells
  • Macrophages
  • T cells

Question 38

Question
What is the main effect of T reg cells?
Answer
  • Recruiting neutrophils
  • Activating macrophages
  • Triggering B cell proliferation and antibody secretion
  • Inhibition of immune response

Question 39

Question
What is the main effect of TH2 cells?
Answer
  • Recruiting neutrophils
  • Activating macrophages
  • Triggering B cell proliferation and antibody secretion
  • Inhibition of immune response

Question 40

Question
What is the main effect of TH1 cells?
Answer
  • Recruiting neutrophils
  • Activating macrophages
  • Triggering B cell proliferation and antibody secretion
  • Inhibition of immune response

Question 41

Question
What is the main effect of TH17 cells?
Answer
  • Recruiting neutrophils
  • Activating macrophages
  • Triggering B cell proliferation and antibody secretion
  • Inhibition of immune response

Question 42

Question
Which cytokine(s) tend to be released by TH17 cells?
Answer
  • IL-7
  • IL-17
  • TGF-beta
  • IL-10

Question 43

Question
Which cytokine(s) tend to be released by TH1 cells?
Answer
  • IL-7
  • IL-10
  • IFN-gamma
  • TGF-beta

Question 44

Question
Which cytokine(s) tend to be released by TH2 cells?
Answer
  • IL-4
  • TNF-a
  • TNF-b
  • PGD2

Question 45

Question
Which cytokine(s) tend to be released by CD8+ cells?
Answer
  • IFN-gamma
  • TNF-a
  • TGF-b
  • IL-4

Question 46

Question
What feature on T cells helps to induce proliferation B cells?
Answer
  • CD40
  • CD40 Ligand
  • mIgM
  • CD45

Question 47

Question
B cells have complement receptors.
Answer
  • True
  • False

Question 48

Question
As well as perforin and granzyme to kill target cells, NK cells have...
Answer
  • NK Cytotoxic factor
  • CD40 Ligand
  • Major basic protein
  • Lyophosphatase

Question 49

Question
Interferon gamma is produced by NK cells - what is its function?
Answer
  • Activate phagocytes
  • Activates B cells
  • Induces proliferation of T cells

Question 50

Question
NK cells have a T cell receptor.
Answer
  • True
  • False

Question 51

Question
T cells are the most abundant lymphocytes.
Answer
  • True
  • False
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