Question 1
Question
The microorganisms that do not have a nucleus in their cells are called
Answer
-
decomposers
-
prokaryotes
-
pathogens
-
eukaryotes
-
fermenters
Question 2
Question
Koch's postulates are criteria used to establish that
Question 3
Question
A fat is called____ if all carbons of the fatty acid chain are single bounded to 2 other carbons and 2 hydrogens
Question 4
Question
The building blocks of an enzyme are
Question 5
Question
ATP is best described as
Question 6
Question
Which of the following is not a characteristic of a prokaryote?
Answer
-
Its DNA is not encased in a membrane
-
It has a cell wall made of peptidoglycans or other distinct chemicals
-
it does not have membrane-bound organelles
-
Its DNA is wrapped around histones
-
All of these are characteristics of prokaryotes
Question 7
Question
Peptiodoglycan is a unique macromolecule found in bacterial
Answer
-
cell walls
-
cell membranes
-
capsules
-
smile layers
-
inclusions
Question 8
Question
The bacterial chormosome
Answer
-
is located in the cell membrane
-
contains all the cell's plasmids
-
is part of the nucleoid
-
forms a single linear strand of DNA
-
all of the choices are correct
Question 9
Question
The function of bacterial endospores is
Answer
-
to convert gaseous nitrogen to a usable form for plants
-
reproduction and growth
-
protection of genetic material during harsh conditions
-
storage of excess cell materials
-
to act as sites for photosynthesis
Question 10
Question
Two major structures that allow bacteria to adhere to surfaces are ___ and ___
Answer
-
pili, ribosome
-
fimbrae, capsules
-
lipoplysaccharides, techoic acids
-
actin filaments, phospholipid membranes
-
actin filaments, ribosomes
Question 11
Question
As a triage nurse in the ER, you begin the assessment of an elderly patient complaining of blood diarrhea and severe stomach cramps. You find the patient has a fever of 104 as well, and is show signs of dehydration. IV fluids are administered while further analysis of the patient continues
Gram staining reveals the presence of gram-negative bacilli in the patient's stool. Thinking about the patient's spike in temperature, you understand now how this bacterium could cause a fever. WHich of the following is the correct explanation?
Answer
-
Gram-negative bacteria have a thick peptidoglycan layer which confers their ability to cause fever
-
Gram-negative bacteria have 2 periplasmic spaces which enhances their ability to cause fever
-
Gram-negative bacteria have teichoic acid in their outer membrane which confer their ability to cause fever
-
Gram-negative bacteria have lipoplysaccharide in their outer membrane, and the lipid portion confers their ability to cause fever
Question 12
Question
The endosymbiotic theory has been developed to explain the mergence of eukaryotes. The eukaryotic mitochondrion most resembles a bacterial cell due to
Answer
-
an other membrane which is similar to the Gram-negative outer membrane
-
70S ribosomes rather than 80S ribosomes
-
the presence of its own DNA molecule
-
all of the above
-
none of the above
Question 13
Question
Which of the following is found in eukaryotic cells but not in prokaryotic cells
Question 14
Question
Which of the following is not a function of the eukaryotes glycocalyx
Question 15
Question
The site of ribosomal RNA synthesis is the
Answer
-
ribosome
-
nucleolus
-
nucleus
-
Golgi apparatus
-
Lysosome
Question 16
Question
You begin your 10 hour shit at the infusion center at the local cancer center. Mrs. Overrocker has be coming in every Wednesday at 10:00 am for the past 3 weeks for her infusion of chemotherapy. She complains that her mouth hurts. A visual examination reveals a white film covering the inside of her cheeks and her tongue. You swab the inside of her mouth for microscopic analysis.
You look closely and see that some of the cells are producing filamentous structures called hyphae. A term referring to a yeast able to exist in a yeast or hyphal form is
Answer
-
dioecious
-
dimorphic
-
dichotomous
-
diurnal
Question 17
Question
The term chemoheterotroph refers to an organisms that
Answer
-
uses CO2 for its carbon source
-
must obtain inorganic compounds for its energy source
-
gets energy from sunlight
-
gets energy by oxidizing chemical compounds
-
does not need a carbon source
Question 18
Question
The movement of substances from lower to higher concentration across a semi-permeable membrane that must have a specific protein carries and cell expenditure of energy is called
Answer
-
facilitated diffusion
-
diffusion
-
active transport
-
osmosis
-
endocytosis
Question 19
Question
When whole cells or large molecules in solution are engulfed by a cell, this endocytosis is specifically termed
Answer
-
pinocytosis
-
phagocytosis
-
facilitated transport
-
facilitated diffusion
-
exocytosis
Question 20
Question
Cultures of a bacterial species were incubated on the shelf of a refrigerator, out on a lab bench top, on the shelf of a 37 degree incubator, and on the shelf of a 50 degrees incubator. After incubation. there was no growth at 37 degrees and 50 degrees, slight growth out on the bench top, and abundant growth at refrigeration. What term could be used for this species?
Answer
-
halophile
-
mesophile
-
anaerobe
-
psychorophile
-
capnophile
Question 21
Question
The E. coli that normally live in human large intestine and produce vitamin K for the body to use would best be termed a ____ relationship
Question 22
Question
The time interval from parent cell to two new daughter cells is called
Answer
-
binary fission
-
growth curve
-
generation time
-
death phase
-
culture time
Question 23
Question
The process that destroys or removes all microorganisms and microbial forms including bacterial endospores on inanimate objects is
Answer
-
disinfection
-
sterilization
-
antisepsis
-
sanitization
-
degermation
Question 24
Question
Microbial death occurs when there is
Answer
-
no movement
-
no reproduction
-
a change in appearance
-
a decrease in size
-
all of these occur
Question 25
Question
Ethylene oxide is
Answer
-
sporicidal
-
only effective with high heat
-
the active agent in household bleach
-
used as an antiseptic against anaerobes
-
a halogen
Question 26
Answer
-
broken down in reactions that require energy input
-
proteins that function as catalysts
-
Used up in chemical reactions
-
not need for catabolic reactions
-
all of the choices are correct
Question 27
Question
Each of the following is true of enzymes except
Answer
-
they can be used over and over
-
they may or may not require cofactors
-
their active site is specific to the substrate
-
they increases the activation energy of a reaction
-
all of the choices are true of enzymes
Question 28
Question
Denaturing an apoenzyme will destroy the three-dimensional shape of the protein, making it nonfunctional
Question 29
Question
Enzymes that catalyze moving a phosphate from one substrate to another are called
Answer
-
phosphotransferases
-
oxidoreductases
-
decarbosylases
-
aminotransferases
-
ligases
Question 30
Question
Each of the following are denaturing agents except
Question 31
Question
The breakdown of petiodglycan to N-acetylmuramic acid, N-acetlyglucoasmine, and peptides is an example
Answer
-
anabolism
-
catabolism
-
phosphorylation
-
fermentation
-
synthesis
Question 32
Question
During aerobic cellular respiration, the final electron acceptor is
Answer
-
pryruvic acid
-
oxygen
-
nitrate
-
cytochorome c
-
FAD
Question 33
Question
In the cell, energy released by electrons is often used to phosphorylate
Answer
-
ATP
-
ADP
-
pyruvic acid
-
oxygen
-
NAD
Question 34
Question
In addition to electrons, which of the following is also involved in electron transfer
Answer
-
ADP
-
Glucose
-
carbon
-
hydrogen
-
carbon dioxide
Question 35
Answer
-
uses 2 ATPs, produces 2 ATPs, and requires oxygen
-
uses 2 ATPs, produces 4 ATPs, and requires oxygen
-
uses 2 ATPs, produces 4 ATPs, and without using oxygen
-
uses 2 ATPs, produces 2 ATPs, and without using oxygen
-
None of the choices are correct
Question 36
Question
The formation of citric acid from oxaloacetic acid and an acetyl group begins
Question 37
Question
The majority of reduced NAD is produced in
Question 38
Question
Each NADH that Enter the electrons transport system gives rise to ____ ATP
Question 39
Question
Each FADH2 from the Krebs cycle enter the electron transport system and gives rise to ____ ATPs
Question 40
Question
During which of the phases of cellular respiration is the majority of ATP formed?
Question 41
Question
ATP syntase is a complex enzyme needed for oxidative phosphoylation
Question 42
Answer
-
requires an organic electron acceptor
-
requires oxygen
-
only occurs in aerobic organisms
-
is equivalent to aerobic respiration in ATP production
-
none of the choices are correct
Question 43
Question
Formation of peptide bounds between amino aids to build a polypeptide would be called
Answer
-
anabolism
-
phosphorylation
-
fermentation
-
exergonic
-
glycolysis
Question 44
Question
Building block molecules for biosythtic pathways come from the cell's catabolic pathways and from the environment
Question 45
Question
A 67-year-old patent with sever sepsis undergoes a full infectious work-up upon admittance to the intensive care unit. Culture of urine, blood, sputum, and cerebral spinal fluid are obtained. The cultures do not yield a specific organisms, so further analysis of the sample is done to determine the characteristics of the microorganism. The metabolic processes are analyzed in the lab.
The organisms is found to grow throughout the entire tube of broth media. Which of the following terms dest describes the oxygen requirement of this organism?
Answer
-
obligate aerobe
-
microaerophile
-
facultative anaerobe
-
obligate anaerobe
Question 46
Question
A 67-year-old patent with sever sepsis undergoes a full infectious work-up upon admittance to the intensive care unit. Culture of urine, blood, sputum, and cerebral spinal fluid are obtained. The cultures do not yield a specific organisms, so further analysis of the sample is done to determine the characteristics of the microorganism. The metabolic processes are analyzed in the lab.
The organisms is found to grow throughout the entire tube of broth media. Which of the following terms dest describes the oxygen requirement of this organism?
Answer
-
obligate aerobe
-
microaerophile
-
facultative anaerobe
-
obligate anaerobe
Question 47
Question
A 67-year-old patent with sever sepsis undergoes a full infectious work-up upon admittance to the intensive care unit. Culture of urine, blood, sputum, and cerebral spinal fluid are obtained. The cultures do not yield a specific organisms, so further analysis of the sample is done to determine the characteristics of the microorganism. The metabolic processes are analyzed in the lab.
Biochemical testing reveals that the organisms further reduces nitrate to produce nitrous oxide. Based upon this byproduct, which of the following is the most likely catabolic pathway utilized by this organism?
Question 48
Question
What is the maximum net yield of ATP from anaerobic respiration?
Question 49
Question
Which of the following macromolecules, when catabolized, COULD release carbon, sulfur and nitrogen
Answer
-
nucleic acids
-
proteins
-
carbohydrates
-
lipids
-
all of the above
Question 50
Question
Which of the following is not a characteristic of a prokaryote
Answer
-
Its DNA is not encased in membrane
-
it has a cell wall made of peptidoglycans or other distinct chemicals
-
its does not have membrane-bound organelles
-
its DNA is wrapped around histones
-
all of these are characteristics or prokaryotes
Question 51
Question
According to the current taxonomy or organisms, which of the following is not considered a domain
Question 52
Question
Each ____ is a specific segment of the DNA with the code fro production of one functional product
Answer
-
intron
-
exon
-
gene
-
operator
-
triplet
Question 53
Question
The DNA of microorganisms is made up of subunits called
Answer
-
histones
-
amino acids
-
nucleotides
-
mRNA
-
polymerases
Question 54
Question
Base pairs in DNA are held together by ____ bonds
Answer
-
peptide
-
nonpolar covalent
-
polar covalent
-
hydrogen
-
sulfhydryl
Question 55
Question
The duplication of a cell's DNA is called
Answer
-
mitosis
-
replication
-
transcription
-
translation
-
mutation
Question 56
Question
During replication, each parent DNA strand sever as a ____for synthesis of new DNA strands
Answer
-
Copy point
-
Template
-
Comparison molecule
-
scaffold
-
reservior
Question 57
Question
Semi- conservative replication refers to
Answer
-
each base bonding at the 1' position of the sugar
-
a purine always bonding to a pyrimindine
-
one helix strand that runs from the 5' to 3' direction and the other strand runs from the 3' to 5' direction
-
the original parent DNA strand and one newly synthesized DNA strand compromising a new DNA molecule
-
None of the choices are correct
Question 58
Question
The site where the old DNA strands separate and new DNA strands will be synthesized is called the
Answer
-
primer
-
Okazaki fragments
-
template
-
rolling circle
-
replication fork
Question 59
Question 60
Question
Replication of DNA begins at a/an
Answer
-
guanine-cytosine rich area
-
uracil-adenine rich area
-
adenine-thymine rich area
-
adenine-cytosine rich area
-
guanine-adenine rich area
Question 61
Question
RNA molecules differ from DNA molecules because only RNA
Question 62
Question
All of the following pertain to transcription except
Answer
-
occurs on a ribosome in the cytoplasm
-
occurs before translation
-
requires RNA polymerase
-
requires a template DNA strand
-
proceeds in the 5' to 3' direction of the growing mRNA molecule
Question 63
Question
Which of the following is incorrect about transfer RNA
Answer
-
has a bottom hairpin loop with an anticodon
-
as anticodon is complementary to a codon
-
contains a binding site for an amino acid
-
the initiator tRNA that bind to the P site has the anticodon UAC
-
initiator tRNA is bacteria carries tryptonphan
Question 64
Question
The following pertains to ribosomes during protein synthesis exceot
Answer
-
participate in both transcription and translation
-
participate only in translation
-
bind to the 5' end of mRNA by their small subunit
-
use their large subunit to supply enzymes for peptide bonding
-
shift to the right along the mRNA strand from one codon to the next
Question 65
Question
Which of the following is not associated with a prokaryotic ribosome?
Question 66
Question
which is incorrect about inducible operons
Answer
-
have genes turned off by a build up of end product
-
are often for catabolic pathways
-
are normally turned off
-
are turned on by the substrate of the enzyme
-
include the lac operon
Question 67
Question
The operon segment composed of the gene that codes fro a protein capable of repression the operon is called the
Question 68
Question
Synthesis of an inducible enzyme requires
Answer
-
repressor alone bound to operator
-
substrate bound to repressor
-
substrate bound to promoter
-
corepressor and repressor binding to operator
-
none of the choices are correct
Question 69
Question
Gene regulation can involve a protein repressor that blocks ____ from initiating transcription
Answer
-
RNA polymerase
-
DNA polymerase I
-
DNA polymerase III
-
mRNA
-
rRNA
Question 70
Question
A mutation that changes a normal codon to a stop codon is called a
Answer
-
point mutation
-
silent mutation
-
back mutation
-
missense mutation
-
nonsense mutation
Question 71
Question
A frame shift is caused by ____ mutations
Answer
-
missense and insertion
-
missense and nonsense
-
nonsense and deletion
-
deletion and insertion
-
insertion and nonsense
Question 72
Question
A bacteriophage transfers DNA of the pervious host to the current host. This is an example of
Question 73
Question
The jumping of a gene from one location to another is done by
Answer
-
conjugation
-
transposons
-
transformation
-
transduction
-
transmission
Question 74
Question
A 59-year-old female has been diagnosed with E. coli infection following the consumption of contaminated meat. THE patient is exhibiting a high fever, severe abdominal cramping, and diarrhea. As the RN, you provide supportive care and fluid resuscitation as ordered. You are familiar with the E. coli bacterium, and provide education to the patient and her family regarding the genetics of this bacterium.
As the RN, you instruct the family that the transfer of genetic material can involve contact between 2 bacterial cells, DNA can pass from one cell to the other through a pilus during this process, which is called
Answer
-
transformation
-
conjugation
-
specialized transduction
-
generalized transduction
Question 75
Question
In gram-negative bacteria, like E. coli, the fertility factor is a plasmid possessed by the bacterium that will donate its DNA to a recipient cell. Which of the following statements, by the patient, demonstrates understanding of this plasmid?
Answer
-
"it is a large, double-stranded linear piece of DNA"
-
"it is found in F- cells only"
-
"it controls the process of transduction in bacterial cells"
-
"It encodes the information to create a pilus"
Question 76
Question
You also indicate to the patient that genetic information can be acquired by bacterial cells in other ways. Which of the following is a correct statement regarding these processes?
Answer
-
"transformation requires that formation of a pilus for genetic exchange to occur"
-
"transposition involves the transfer of genetic information to bacterial cells directly from their environment"
-
"Transfection is a phenomenon of prokaryotic cells"
-
Transduction involves the transfer of genetic information from a bacteriophage to a bacterial cell"
Question 77
Question
Virus capsids are made from subunits called
Answer
-
envelopes
-
spikes
-
capsomeres
-
prophages
-
peplomers
Question 78
Question
The core of every virus particles always contains
Answer
-
DNA
-
capsomeres
-
enzymes
-
either DNA or RNA
-
DNA and RNA
Question 79
Question
Viruses with ___ sense RNA contain the correct message for translation, while viruses with ___ sense RNA must first be converted into a correct message
Question 80
Question
In general, most DNA viruses multiply in the host cell's ____, while most RNA viruses multiply in the host cell's ___
Question 81
Question
Host range of a virus is limited by
Answer
-
type of nucleic acid in the virus
-
age of the host cell
-
type of host cell receptors on the cell membrane
-
size of the host cell
-
all of the choices are correct
Question 82
Question
The human body typically begins to be colonized by its normal biota
Answer
-
before birth, in urtero
-
during and immediately after birth
-
when a child first goes to school
-
when an infant get its first infectious disease
-
during puberty
Question 83
Question
Pathogenic microbes that cause disease in healthy people are called
Answer
-
opportunistic pathogens
-
normal biota
-
indigenous biota
-
true pathogens
-
micropathogens
Question 84
Question
Virulence factors include all the following except
Answer
-
capsules
-
ribosomes
-
exoenzymes
-
endotoxins
-
exotoxins
Question 85
Question
The time from when pathogen first enters the body and begins to multiply, until symptoms first appear is the
Question 86
Question
Which is mismatched
Answer
-
secondary infection- infection spread to several tissue sites
-
mixed infection- several agents established at infection site
-
acute infection- rapid onset of severe, short-lived symptoms
-
local infection-pathogen remains at or near entry site
-
toxemia- pathogen's toxins carried by the blood to target tissues
Question 87
Question
The chemical found in tears and saliva that hydrolyzes the petidoglycan in certain bacterial cell walls is
Answer
-
lactic acid
-
hydrochloric acid
-
lysozyme
-
histamine
-
bile
Question 88
Question
A properly functioning immune system is responsible for
Answer
-
surveillance of the body
-
recognition of foreign material
-
destruction of foreign material
-
all of the above choices are correct
-
only recognition of foreign material and destruction of foreign material are correct
Question 89
Question
The main function of the reticuloendothelial system is to provide
Answer
-
surveillance cells
-
a connection between tissues and organs
-
filtration of extracellular fluid
-
filtration of blood
-
all of the choices are correct
Question 90
Question
During what process are hyprochlorite and hydrogen peroxide produced to destroy bacteria and inhibit viral replication
Answer
-
inflammation
-
phagocytosis
-
interferon production
-
complement production
-
bradykinin
Question 91
Question
which protein can be produced by a virus-infected cell, in order to communicate with other cells the need to produce antiviral proteins
Answer
-
complement
-
albumin
-
interferon
-
histamine
Question 92
Question
The progeny cells of a B-cell clone are called
Answer
-
antibodies
-
sensitized T cells
-
activated macrophages
-
plasma cells
-
bursa cells
Question 93
Answer
-
posses MHC antigens for recognizing self
-
have membrane receptors that recognize foreign antigens
-
gain tolerance to self by destruction of lymphocytes that could react against self
-
develop into clones of B and T cells with extreme variations of specificity
-
all of the choices are correct
Question 94
Question
Cytotoxic T cells
Answer
-
are activated by antigens
-
lack specificity for antigens
-
secrete granzymes and perforins that damage target cells
-
secrete interleukin-2 to stimulate B and T cells
-
all of the choices are correct
Question 95
Question
Edward Jenner's work involved
Answer
-
inoculation of dried pus from small pox pustules into a person to stimulate immunity
-
development of passive immunotherapy
-
development of an immunization to protect people again cowpox
-
immunization using a related, less pathogenic organisms to give protection agains a more pathogenic one
-
all of the choices are correct
Question 96
Question
Acellular vaccines and subunit vaccines
Answer
-
contain modified bacterial exotoxin molecules
-
are always genetically engineered
-
contain select antigenic components of a pathogen rather than whole cells or viruses
-
confer passive immunity
-
utilize DNA strands that will produce the antigen
Question 97
Question
Selctive toxicity refers to
Answer
-
damage to pathogenic organisms
-
damage to prokaryotic cell membranes
-
damage to the target organisms but not host cells
-
damage to nucleic acids
-
none of the choices are correct
Question 98
Question
Joseph is a 6-year-old male presenting to your pediatric office with chickenpox. He had had his infection for about 1 week, and his mom is concered about Joseph's 8- year-old sister, Judith, because she had a long painful infection of chickenpox 2 years before. Of note, Joseph was not vaccinated against chickenpox when he was younger, because his mom did not think it was that serious of a virus and she wanted to spare him the extra injection.
Which of the following explanations tells you why Joseph became infected with chickenpox in the first place?
Answer
-
he should not have been infected because he had passive natural immunity from breastfeeding as a baby.
-
His mother should have had gamma globulin administered so he would have had passive artificial immunity.
-
There is no way he could have been protected from the infection, since he did not recieve active artificial immunity through the form of a vaccine
-
he probably has a primary immunodeficiency disease, otherwise there is no reason humans should be infected with chickenpox
Question 99
Question
The cellular basis for bacterial resistance to antimicrobials include
Answer
-
bacterial chromosomal mutations
-
synthesis of enzymes that alter drug structure
-
prevention of drug entry into the cell
-
alteration of drug receptors on cell targets
-
All of the choices are correct
Question 100
Question
A superinfection results from
Answer
-
build up of a dug to toxic levels in patient
-
the wrong drug administered to patient
-
an immune system reaction to the drug
-
decrease in most normal flora with overgrowth of an unaffected species
-
all of the choices are correct