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Microorganisms and biotechnology

Sara Bean

  • Biotechnology involves applying biological organisms or enzymes to the synthesis, breakdown or transformation of materials in the service of people
  • Most commonly used organisms in biotechnology are fungi, particularly yeasts, and bacteria which are more useful in the newer technologies

The use of microorganisms

  • Most biotechnologies involve enzymes in a manufacturing process and the most stable, convenient and effective form of the enzymes is a whole microorganism
  • Used because:
    • No welfare issues to consider - only need optimum conditions for growth
    • Enormous range of them which are capable of carrying out reactions that can be used
    • Can be genetically engineered to carry out reactions they wouldn't naturally
    • Short life cycle and rapid growth rate
    • Nutrient requirements are often cheap and simple
    • All they need is an oxygen supply, relatively low temperatures and food and bring their own enzymes so the processes are kept cheap

Indirect food production

  • If the conditions aren't ideal the microorganisms don't grow properly and they don't work as effectively
  • Conditions that are ideal for helpful microorganisms may also be ideal for the food to spoil or pathogens to grow so it has to be sterile
  • Some people have ethical issues with the use of GM organisms
  • Baking
    • Yeast + sugar + water to respire aerobically
    • Carbon dioxide produced makes the bread rise
    • Yeast cells are killed during cooking
  • Brewing
    • Yeast respires anaerobically to make ethanol
    • GM yeasts ferment at lower temperatures to make the process cheaper
  • Cheese-making
    • Bacteria are used
    • They feed on the lactose in milk to change the texture and taste
    • Inhibiting the growth of the bacteria stops the milk going off
  • Yoghurt-making
    • Bacteria are used
    • Often Lactobacillus bulgaricus forms ethanal and Streptococcus thermophilus forms lactic acid
    • Both produce extracellular polymers that give the yoghurt its smooth, thick texture

Direct food production

  • Facing protein shortages, scientists have developed ways to use microorganisms to directly produce edible proteins
  • ^^ is single-cell protein (SCP)
  • Most commonly known one is Quorn
  • ^ single-celled fungus that is grown in large fermenters with glucose syrup
  • They are combined with albumen then compressed and formed into meat substitututes
  • High in protein and low in fat
  • Yeasts, algae and bacteria can be used to grow proteins that match animal proteins as well as plant proteins 
  • ^^ can be grown on almost anything, are cheap and low in fat but people have reservations about food grown on waste
  • SCP are used more to feed animals that we prefer to eat like cattle and pigs

Advantages of using microorganisms to produce human food

  • Produce proteins faster than plants or animals
  • Have a higher protein content and lower fat content
  • They use a range of waste materials which reduces the cost
  • Can be genetically modified easily
  • Not dependent on weather or mating cycles
  • No welfare issues
  • Can be made to taste like anything

Disadvantages of using microorganisms to produce human food

  • Some microorganisms can also produce toxins if the conditions aren't optimum
  • Have to be separated from the nutrient broth and processed to make the food
  • Need sterile conditions which adds to the cost
  • Many people have concerns over eating GM foods
  • The protein has to be purified to make sure its not contaminated
  • People dislike the idea of eating food made on waste
  • Has little natural flavour - have to add additives

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