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Excitable Cells

J yadonknow Englisch 15 Karten

Karten in diesem Stapel (15)

  1. 1What is Vm?Resting membrane potential
  2. 2Origin of VmUneven distribution of ions across a membrane
  3. 3What maintains Vm?Na+/K+ pumps
  4. 4Nernst limitationsDeals with 1 ion at a time and assumes it's in electrochemical equilibrium
  5. 5Nernst EquationEx = 61og[X]o/[x]i mV
  6. 6GHK equationVm = pk[K+]out+p(Na)[Na+]out+pCl[Cl-]in
    -----------------------------------------------------
    pK[K+]in + pNa[Na+]in+pCl[Cl-]out
  7. 7Why is Cl in/out?As it has a negative valence
  8. 8What is conductance and indirect measurement of?Permeability of a channel when a specific voltage is applied to a membrane
  9. 9How does an uneven distribution of charge lead to an action potential?When the influx of Na+ surmounts the rate at which the cell can release K+ to compensate then an action potential is triggered and Vm becomes a function of [Na+]'
  10. 10terminationChannel inactivation of Na+ halts inward flow of Na+
    K+ passively flows out, repolarising the cell.
  11. 11Why is there an undershoot?As K+ channels open and close slowly, the increased K+ permeability is slow to cease
  12. 12What is ARP?Absolute refractory period
  13. 13Yeah, but what IS ARP?Period after an AP in which channels are deactivated and can't be opened
  14. 14What is RRP?After ARP Na+ channels begin to recover from inactivation
    Difficult to trigger an AP as Na+ channels still recovering
  15. 15What is capacitance an indirect measurement of?Voltage passing through a resistor
    Like protestors running through a riot squad, some of them will be pushing against the riot men whilst the few that break through are the conductance

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Karteikarten am Excitable Cells, erstellt von J yadonknow am 28/05/2018.
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J yadonknow
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