Karteikarten
Exam 1 modules 1-4

Karten in diesem Stapel (131)
- 1The nervous system

- 2Neuron morphology

- 3Dendrites

- 4Neuronal polarity

- 5Transmission of signals between neurons in a simple neuronal circuit

- 6Reflex arc example

- 7Transmission of electrical signals BETWEEN neurons

- 8Graded electrical signals vs all or no signals

- 9Describe the process of transmission of electrical signals within the neuron

- 10What do graded signals depend on and what do all or no signals depend on?

- 11Electric potential vs membrane potential

- 12Ion gradient across membrane of typical cell

- 13Measuring membrane potential when both electrodes in saline bath

- 14Measuring membrane potential when electrode penetrates cell

- 15Passive electrical properties of cell membrane

- 16Stimulus current

- 17Membrane voltage in response to stimulating currents in excitable cells

- 18Resistance, conductance, and capacitance are what and responsible for what-are the passive electrical properties of the cell membrane
-are necessary for maintaining the cell's membrane potential
-give the membrane its ability for time-dependent responses to stimulation and voltage changes - 19What is electrochemical potential dependent on?

- 20A chamber filled with KCl with 2 compartments separated by a membrane that is permeable to + but not Cl- with equal concentration

- 21A chamber filled with KCl with 2 compartments separated by a membrane that is permeable to + but not Cl- with compartment I having more KCl

- 22Electrochemical equilibrium vs equilibrium potential

- 23If KCl concentration in compartment I is higher than II does the voltage change and is energy spentA change in voltage
No energy spent to generate or maintain it - 24Resting Membrane potential

- 25Na+/K+ pump vs. K+ leak channel

- 26Na+/K+ pump illustrated

- 27Action Potential

- 28Action potentials in excitable cells sequence of events

- 29Voltage-gated Na+ channels and the action potential

- 30Changes in Vm and ionic conductances during an action potential

- 31Threshold potential

- 32IsopotentialSame potential everywhere
ex. the potential sensed by the intracellular electrode does not change as the tip is advanced further into the cell because in the resting state the cytoplasm is isopotential - 33Phasic

- 34Tonic

- 35Propagation of action potentials along an axonThe opening and closing of voltage-gated Na+ channels along the axon are sequential
-the current that flows through one Na+ channel provides the stimulus (voltage charge) to open the next
-electrodes can measure at different points - 36The initiation of action potentials

- 37The refractory periods after an action potential

- 38Alternation of graded and all-or-none electrical signals during neurotransmission in neuronal circuit

- 39Transmission of the receptor potential through the neuronal soma

- 40Measuring the decay of a graded signal during an electronic transmission vs the propagation of an all-or-none signal along an axonThe graded signal gets weaker further away from the injection site, signals without action potentials are subject to decay
All-or-none signal, if the stimulus current is strong, APs are induced, the amplitude does not vary with their positions, and voltage-gated channels continue to open throughout the length of the axon - 41Changes in adjacent voltage-gated Na+ channelsThe propagation of the action potential in one direction
-an inward flow of Na+ causes a local membrane polarity reversal (a depolarization) around the open channel, the resulting change in Vm acts as the threshold potential that opens the adjacent channel, and the first channel switches to inactive, then onward to the next, the first becomes closed, the second inactive, and the third open - 42Ion channels and the action potential -resting -rising -falling -recovery

- 43Glial Cells

- 44Myelination of CNS axons by oligodendrocytes

- 45Nodes of Ranvier

- 46The cell membrane as a capacitor

- 47Consequences of myelination

- 48Saltatory conduction of APs in the myelinated axons

- 49DemyelinationDemyelination disrupts the velocity of electrotonic transmission through the axon and the overall speed of electrical conduction and neurotransmission

- 50Communication between neuronsSynapse: the point of physical interaction and neurotransmission between the presynaptic and postsynaptic neurons
Two types
1. electrical
2. chemical - 51Electrical Synapse

- 52Chemical synapse

- 53Chemical synaptic transmission

- 54Changes in Vm and ionic conductances during an action potential

- 55Why are chemical synapses the preferred mode of neurotransmission in the nervous system over electrical?Chemical is slower but they can be regulated so they are preferred over faster electrical that are faster
- 56How are chemical signals regulated?The signal is terminated by removing the NT from the synapse
1. reabsorption (serotonin, dopamine)
2. enzymatic degradation (acetylcholine) - 57ProzacProzac blocks the reabsorption of serotonin by the presynaptic cell
(Neurotransmitter regulated by reabsorption example) - 58CocaineCocaine inhibits the elimination of dopamine from the synapse by blocking its reabsorption
-due to excessive stimulation the number of dopamine receptors in the postsynaptic membrane decreases and the synapse is less active when the drug is removed (drug addiction) - 59Fast chemical synaptic transmission

- 60Slow chemical synaptic transmission

- 61Innervation of a frog muscle

- 62The neuromuscular junction

- 63The motor endplate

- 64Acetylcholine

- 65Endplate potentials at several distances from the endplate

- 66Reversal potential

- 67Measuring the reversal potential

- 68Excitatory vs inhibitory

- 69Excitatory and inhibitory postsynaptic currents and potentials

- 70Specialized receptor cells

- 71Properties of Stimuli

- 72What does the ability to distinguish all colors depend on?The ability to distinguish all colors depends on the combined sensitivities if just 3 types of cone photoreceptor cells
Blue
Green
Red - 73Not all receptor cells are ___ but ALL receptor cells ________Not all receptor cells are neurons but all receptor cells produce neurotransmitters (only neurons have action potentials)
- 74Transmission of sensory info to the CNS Pattern 1: the soma of the sensory neuron is close to the site where the stimulus is received and far from the CNS

- 75Transmission of sensory info to the CNS Pattern 2: the soma of the sensory neuron is close to the site where the stimulus is received and close to the the CNS

- 76Transmission of sensory info to the CNS Pattern 3: non-neuronal receptors

- 77Transduction

- 78Signal amplification in odorant chemoreception

- 79Conversion of the receptor potential into APs

- 80Neuronal receptor vs non-neuronal receptor pathway

- 81Limitations on stimulus strength1. limit on receptor current: there is a finite number of ion channels on the membrane (opening them all is the limit)
2. Limit on the amplitude of the receptor potential: it can not exceed the reversal potential for the ion current
3. Limit on the frequency of APs: APs can not occur during refractory period
Dynamic Range: the range of intensity that a receptor system can decode (the range of stimulus it will respond to) - 82Limited by reversal potential graphed

- 83Limited by refractory period graphed

- 84Sum of both Refractory period and reversal potential properties

- 85Baseline Frequency

- 86Modifying AP frequency by the stimulus

- 87Chemoreceptors

- 88Structure of the vertebrate taste bud

- 89Transduction mechanisms of salty (some sour) taste quality

- 90Transduction mechanisms of other sours (some bitter) taste quality

- 91Transduction mechanisms of other bitters taste quality

- 92Transduction mechanisms of sweet taste quality

- 93Transduction mechanisms of slightly bitter and some sweet taste quality

- 94Where is taste reception processed? Where is smell and pheromone reception processed?Taste reception is processed at the somatosensory cortex
Smell and pheromone reception are both processed at the olfactory cortex (very small in humans) - 95Olfactory organs

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- 98Olfactory Epithelium

- 99Odorant receptor proteins

- 100Axons from nasal and vomeronasal epithelia

- 101The vomeronasal organ (VNO)

- 102Vomeronasal in squamates

- 103The vomeronasal organ in mammals

- 104The function of PLC in pheromone reception

- 105Drosophila explained

- 106Drosophila illustrated and graphed

- 107What is a hair cell? What does it do?

- 108Hair cell structureThe typical hair cell has 1 kinocilium and 20 stereocilia on its apical surface, the displacement of the entire bundle results in a Vm across the membrane of the hair cell

- 109Linking filaments between ciliaLinking filaments interconnect the kinocilium and the stereocilia so that mechanical displacement (movement) of one cilium results in the displacement (movement) of all the cilia in a bundle, and the opening of mechanosensitive ion channels
- 110Stimulation of the hair cell graphed

- 111Simulation of hair cell excitatory vs inhibitory

- 112Examples of mechanoreception in vertebrates by hair cells

- 113Hair cells in XenopusHair cells of the lateral-line system in Xenopus
-the cilia are embedded inside the flexible, jellylike cupula, which displaces the cilia of the underlying hair cells in response to water motion
- 114What do human vestibular organs do?1. detect position of body relative to gravity (ex. losing balance)
2. detect acceleration (movement)
3. detect sound/hearing - 115The vertebrate organs of equilibrium in the inner ear

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- 123The organ of Corti

- 124Ion channels on the hair cell stereocilia

- 125—


- 126Frequency sensitivity of the basilar membrane

- 127Insect tympanal ears

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- 129What is the resting voltage of cells?All living cells have a Vrest between -20mv and -100mv due to the passive electrical properties of the membrane
- 130—


- 131What is a local membrane potential reversal also called?Depolarization
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- College Animal Physiology Karteikarten am Exam 1 modules 1-4, erstellt von Bree Bree am 26/08/2022.
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- Bree Bree
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