Ohne Titel

Genetic disorders

mutant allele

change in nucleotides

autosomal disorders

protein function is altered or interrupted

recessive

the individual need to inherit a mutated allele from the father and another from the mother fo the disease to occur

dominant

the defective or mutant allele is dominant over the normal on, that is enough that it´s presented in a parent to show in the offspring

- phenylketonuria

- albinism

- huntington´s disease

Chromosome- linked

X-linked dominant disorders are caused by mutations in genes on the X chromosome, one of the two sex chromosomes in each cell. In females (who have two X chromosomes), a mutation in one of the two copies of the gene in each cell is sufficient to cause the disorder

trisonomy 21 or down syndrome