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Flussdiagramm

Ohne Titel

Nathan Lin Englisch

Inhalt des Flussdiagramms

  1. Prolactin binds to dopamine neurons in hypothalams

  2. JAK2 activated by phosphorylation

  3. Cytosolic tails phosphorylated

  4. STAT5 phosphorylated

  5. STAT5 dimerizes and enters nucleus

  6. STAT5 induces production of tyrosine hydroxylase

  7. Tyrosine hydroxylase makes dopamine

  8. Lactation increases prolactin production

  9. Hyperprolactinemia

  10. High levels of prolactin in blood

  11. Lactation

  12. Suckling upregulates CIS

  13. CIS prevents dimerisation of STAT5

  14. No STAT5 dimer goes to nucleus

  15. No STAT5 induce the production of tyrosine hydroxylase

  16. Dopamine is not secreted by the dopamine neurons in hypothalamus

  17. Dopamine does not bind to dopamine receptor of lactotroph cells

  18. Lactotroph cells produce more prolactin

  19. Prolactin induces more milk synthesis and secretion

  20. Suckling

  21. Stimulates the nipple more

  22. Hypothalamus stimulated more

  23. Posterior pituitary stimulated more

  24. Suckling

  25. Nipple stimulated more

  26. Hypothalamus stimulated more

  27. Posterior pituitary stimulated more

  28. More oxytocin secreted

  29. Myoepithelial cells contract

  30. Milk ejection

  31. Less dopamine (prolactin inhibitor)

    More prolactin releasing hormone

  32. Lactotroph cells secrete more prolactin

  33. Prolactin stimulates epithelial cells

  34. More milk synthesized and secreted

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Beschreibung
Flussdiagramm am Ohne Titel, erstellt von Nathan Lin am 09/06/2018.
Erstellt von
Nathan Lin
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